生物来源
rabbit
质量水平
抗体产品类型
primary antibodies
克隆
polyclonal
表单
liquid
包含
≤0.1% sodium azide as preservative
种属反应性
rat, gerbil, mouse, salamander, chicken, monkey, fish, human
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
avoid repeated freeze/thaw cycles
同位素/亚型
IgG
运输
wet ice
储存温度
−20°C
一般描述
Anti-Cannabinoid Receptor CB₁ (1-77), rabbit polyclonal, recognizes the ~60 kDa CB1 receptor in wide variety of vertebrates. It is validated for use in immunoblotting and with paraffin sections.
Immunoaffinity purified rabbit polyclonal antibody. Recognizes the ~60 kDa CB1 receptor protein.
Recognizes the ~60 kDa CB1 receptor protein.
免疫原
Rat
a recombinant protein consisting of the first 77 amino acids of rat CB₁ receptor
应用
Immunoblotting (1:1000)
Immunocytochemistry (1:100-1:1000)
Paraffin Sections (see comments)
Immunocytochemistry (1:100-1:1000)
Paraffin Sections (see comments)
外形
In PBS, 1 mg/ml BSA, 50% glycerol.
制备说明
Following initial thaw, aliquot and freeze (-20°C).
分析说明
Positive Control
Hippocampal neurons
Hippocampal neurons
其他说明
May also recognize weaker bands at ~23 kDa, ~72 kDa, and ~180 kDa in some tissues. Immunocytochemical staining of living or fixed cultured hippocampal neurons show intense, punctate staining along processes with little staining over cell bodies. Variables associated with assay conditions will dictate the optimal working dilution.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Standard Handling (A)
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储存分类代码
10-13 - German Storage Class 10 to 13
Talita H Ferreira-Vieira et al.
Hippocampus, 24(1), 79-88 (2013-10-12)
It is well known that physical exercise has positive effects on cognitive functions and hippocampal plasticity. However, the underlying mechanisms have remained to be further investigated. Here we investigated the hypothesis that the memory-enhancement promoted by physical exercise relies on
Jean-François Bouchard et al.
Life sciences, 72(16), 1859-1870 (2003-02-15)
The aim of the present study was to assess the contribution of endogenous cannabinoids in the protective effect of ischemic preconditioning on the endothelial function in coronary arteries of the rat. Isolated rat hearts were exposed to a 30-min low
Francesca Guida et al.
Brain, behavior, and immunity, 85, 128-141 (2019-04-07)
Recent evidence points to the gut microbiota as a regulator of brain and behavior, although it remains to be determined if gut bacteria play a role in chronic pain. The endocannabinoid system is implicated in inflammation and chronic pain processing
Rimonabant precipitates anxiety in rats withdrawn from palatable food: role of the central amygdala.
Angelo Blasio et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 38(12), 2498-2507 (2013-06-25)
The anti-obesity medication rimonabant, an antagonist of cannabinoid type-1 (CB(1)) receptor, was withdrawn from the market because of adverse psychiatric side effects, including a negative affective state. We investigated whether rimonabant precipitates a negative emotional state in rats withdrawn from
Dhanush Haspula et al.
Journal of neurochemistry, 139(4), 523-536 (2016-08-17)
Brainstem and cerebellar astrocytes have critical roles to play in hypertension and attention-deficit hyperactivity disorder, respectively. Angiotensin (Ang) II, via the astroglial Ang type 1 receptor (AT1R), has been demonstrated to elevate pro-inflammatory mediators in the brainstem and the cerebellum.
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