219393
Cathepsin S Inhibitor - Calbiochem
Cathepsin S Inhibitor is a slow, tight-binding reversible inhibitor of cathepsin S (Ki = 185 pM). Exhibits 410-fold greater selectivity over cathepsin B (Ki = 76 nM).
别名:
Cathepsin S Inhibitor - Calbiochem, Z-FL-COCHO
质量水平
方案
≥95% (TLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
颜色
pale yellow
溶解性
DMSO: 5 mg/mL
运输
ambient
储存温度
−20°C
一般描述
A dipeptidyl α-keto-β-aldehyde that acts as a slow, tight-binding, highly potent, reversible inhibitor of cathepsin S. Exhibits over 410-fold greater selectivity for cathepsin S (Ki = 185 pM) over cathepsin B (Ki = 76 nM).
A slow, tight-binding reversible inhibitor of recombinant cathepsin S (Ki = 185 pM). Exhibits about 410-fold greater selectivity for cathepsin S compared to cathepsin B (Ki = 76 nM).
生化/生理作用
Cell permeable: no
Primary Target
cathepsin S
cathepsin S
Product does not compete with ATP.
Reversible: yes
Target Ki: 185 pM against cathepsin S
包装
Packaged under inert gas
制备说明
Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
其他说明
Walker, B., et al. 2000. Biochem. Biophys. Res. Commun.275, 401.
Z-Phe-Leu-COCHO • H₂O
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Standard Handling (A)
储存分类代码
10-13 - German Storage Class 10 to 13
法规信息
监管及禁止进口产品
此项目有
David Possamaï et al.
PloS one, 16(12), e0261987-e0261987 (2022-01-01)
Nanoparticles made of the coat protein of papaya mosaic virus (PapMV) and a single-strand RNA were previously shown to be an efficient antigen presentation system for the trigger of cellular immunity. Engineering of PapMV nano with a cytotoxic T lymphocyte
Muzhou Jiang et al.
Journal of neurochemistry, 155(3), 300-312 (2020-04-25)
Lysosomes are known to mediate neurite outgrowth in neurons. However, the principal lysosomal molecule controlling that outgrowth is unclear. We studied primary mouse neurons in vitro and found that they naturally develop neurite outgrowths over time and as they did
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持