219421
Cathepsin L Inhibitor I
The Cathepsin L Inhibitor I, also referenced under CAS 108005-94-3, controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
别名:
Cathepsin L Inhibitor I, Z-FF-FMK
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关于此项目
经验公式（希尔记法）:
C27H27FN2O4
化学文摘社编号:
分子量:
462.51
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
产品名称
Cathepsin L Inhibitor I, The Cathepsin L Inhibitor I, also referenced under CAS 108005-94-3, controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
InChI key
CAILNONEKASNSH-UHFFFAOYSA-N
InChI
1S/C27H27FN2O4/c28-18-25(31)23(16-20-10-4-1-5-11-20)29-26(32)24(17-21-12-6-2-7-13-21)30-27(33)34-19-22-14-8-3-9-15-22/h1-15,23-24H,16-19H2,(H,29,32)(H,30,33)
SMILES string
FCC(=O)C(NC(=O)C(NC(=O)OCc3ccccc3)Cc2ccccc2)Cc1ccccc1
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated
color
white
solubility
DMSO: 20 mM
shipped in
ambient
storage temp.
−20°C
Quality Level
Analysis Note
single spot by TLC
Biochem/physiol Actions
Cell permeable: yes
Primary Target
cathepsin L
cathepsin L
Product does not compete with ATP.
Reversible: no
Disclaimer
Toxicity: Standard Handling (A)
General description
A potent, cell-permeable and irreversible inhibitor of cathepsin L.
A potent, cell-permeable, and irreversible inhibitor of Cathepsin L (Cat. No. 219402 ).
Other Notes
Ravanko, K., et al. 2004. Cancer Res.64, 8831.
Esser, R.E., et al. 1994. Arthritis Rheum. 37, 236.
Shaw, E., et al. 1993. FEBS Lett.334, 340.
Esser, R.E., et al. 1994. Arthritis Rheum. 37, 236.
Shaw, E., et al. 1993. FEBS Lett.334, 340.
Z-Phe-Phe-CH₂F
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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