219426
Cathepsin L Inhibitor II
The Cathepsin L Inhibitor II controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
别名:
Z-FY-CHO
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关于此项目
NACRES:
NA.77
UNSPSC Code:
12352200
Quality Level
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
off-white
solubility
ethanol: 50 mg/mL, DMSO: soluble
shipped in
ambient
storage temp.
−20°C
General description
A potent and selective inhibitor of Cathepsin L (Cat. No. 219402).
Biochem/physiol Actions
Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Other Notes
Woo, J.-T., et al. 1996. Eur. J. Pharmacol. 300, 131.
Z-Phe-Tyr-CHO
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Stephan Quintin et al.
The Journal of biological chemistry, 299(7), 104912-104912 (2023-06-13)
α-synuclein (αS) is an abundant, neuronal protein that assembles into fibrillar pathological inclusions in a spectrum of neurodegenerative diseases that include Lewy body diseases (LBD) and Multiple System Atrophy (MSA). The cellular and regional distributions of pathological inclusions vary widely
Prashant Gaikwad et al.
microPublication biology, 2022 (2023-01-07)
Several studies have indicated a role for cathepsin L (CTSL) proteolytic activity in the nucleus under distinct cellular conditions, including during differentiation, senescence, and quiescence. Here we show that addition of CTSL inhibitors to a cell lysis buffer prevents the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 219426-5MG | 04055977218350 |