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535140

Protease Inhibitor Cocktail III

Animal-Free, liquid, for the inhibition of aspartic, cysteine, serine proteases and aminopeptidases

别名:

Animal free Protease inhibitor

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UNSPSC Code:
12352200
NACRES:
NA.54
Form:
liquid
Solubility:
water: soluble
Storage temp.:
−20°C
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产品名称

蛋白酶抑制剂混合物套装III，无动物源性成分, Protease Inhibitor Cocktail Set III, Animal-Free, is a cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine & serine proteases & aminopeptidases.

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

solubility

water: soluble

shipped in

wet ice

storage temp.

−20°C

General description

六种蛋白酶抑制剂的混合物，对天冬氨酸、半胱氨酸和丝氨酸蛋白酶以及氨基肽酶具有广泛的特异性。建议将该混合物用于哺乳动物细胞和组织提取物。每个小瓶含有100 mM AEBSF、HCl（目录号101500）、80 µM抑肽酶（目录号616371）、5 mM苯丁抑制素（目录号200484）、1.5 mM E-64（目录号324890）、2 mM亮抑蛋白酶肽（目录号108975）和1 mM胃蛋白酶抑制剂A（目录号516482）。以1 ml瓶或一组5 x 1 ml形式提供。

Biochem/physiol Actions

主要靶标
天冬氨酸、半胱氨酸和丝氨酸蛋白酶以及氨肽酶
产物不与ATP竞争。
可逆：否
细胞可渗透性：否

Physical form

溶于1 ml DMSO。

Preparation Note

初次融化后，等分并冷冻（-20°C）。

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

毒性：刺激性（B）

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

存储类别

10 - Combustible liquids

flash_point_f

188.6 °F

flash_point_c

87 °C

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Mitophagy is an important process for removing damaged mitochondria in cells, the dysfunction of which has been directly linked to an increasing number of neurodegenerative disorders. However, the details of mitophagy in prion diseases still need to be deeply explored.
Jia Chen et al.
Virologica Sinica, 35(5), 614-625 (2020-04-22)
Activation of inflammatory cells and upregulations of a number of cytokines in the central nervous system (CNS) of patients with prion diseases are frequently observed. To evaluate the potential changes of some brain cytokines that were rarely addressed during prion
Sungsin Jo et al.
Arthritis research & therapy, 23(1), 301-301 (2021-12-10)
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全球贸易项目编号

货号GTIN
535140-1ML04055977076141
535140-1SET07790788051235