一般描述
Cell-permeable adenylate cyclase inhibitor. Blocks PTH-stimulation of adenylate cyclase (IC50 = 200 µM). Reduces PGE2-induced inhibition of O2·– production.
生化/生理作用
Cell permeable: yes
Primary Target
adenylate cyclase
adenylate cyclase
Product does not compete with ATP.
Reversible: no
Target IC50: 200 µM against adenylate cyclase
警告
Toxicity: Irritant (B)
重悬
Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 2 weeks at 4°C.
其他说明
Talpain, E., et al. 1995. Br. J. Pharmacol. 114, 1459.
Tamaoki, J., et al. 1993. Prostaglandins45, 363.
Fabbri, E., et al. 1991. J. Enzyme Inhib.5, 87.
Goldsmith, B.A. and Abrams, T.W. 1991. Proc. Natl. Acad. Sci. USA 88, 9021.
Tamaoki, J., et al. 1993. Prostaglandins45, 363.
Fabbri, E., et al. 1991. J. Enzyme Inhib.5, 87.
Goldsmith, B.A. and Abrams, T.W. 1991. Proc. Natl. Acad. Sci. USA 88, 9021.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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