Anti-Serotonin Transporter Antibody

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Other species have not been tested.

The antibody reacts with the 70 kDa serotonin transporter protein.

Epitope: Center region

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human serotonin transporter.

Research Category
Neuroscience

Research Sub Category
Ion Channels & Transporters

This Anti-Serotonin Transporter Antibody is validated for use in WB for the detection of Serotonin Transporter.

Western Blot Analysis: 1:1000 dilution of this antibody detected serotonin transporter on human lung lysate.

70 kDa

Replaces: AB1594P

Antigen Affinity Purified

Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.

Store at 2-8°C for 1 year from date of receipt.

Control
Western Blot : Human lung lysate.

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