Anti-FEZ2 Antibody

Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.

KLH-conjugated linear peptide corresponding to human FEZ2.

Detect the FEZ2 protein using this Anti-FEZ2 validated for use in WB & IF.

Immunofluorescence Analysis: 5 µg/mLfrom a representative lot detected FEZ2 in human brain tissue.

Research Category
Neuroscience

Neuroscience

Research Sub Category
Developmental Neuroscience

Neuroregenerative Medicine

Evaluated by Western Blot in 3T3 cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected FEZ2 in 15 µg of 3T3 cell lysate.

~38/50 kDa observed. An uncharacterized band may appear at ~48 kDa in some lysates.

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
3T3 cell lysate

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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