HRNKLMAG-51K-01
MILLIPLEX® Human RANKL Singleplex
Human RANKL Singleplex
别名:
Human RANKL Detection, Human RANKL Magnetic Beads, RANKL Magnetic Bead Kit
产品名称
MILLIPLEX® Human RANKL Singleplex,
species reactivity
human
shipped in
wet ice
Quality Level
description
Human RANKL Singleplex
packaging
pkg of 1 ea
manufacturer/tradename
Milliplex®
assay range
accuracy: 92%, sensitivity: 5.0 pg/mL, standard curve range: 4.88-20,000 pg/mL
technique(s)
multiplexing: suitable
input
cell culture supernatant
serum
detection method
fluorometric (Luminex® xMAP® technology)
storage temp.
2-8°C
General description
Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL) is a pivotal biomarker involved in bone metabolism, immune regulation, and neuroinflammation. Its expression reflects osteoclast activity and has implications in neurodegenerative conditions where bone-immune-brain interactions are relevant. Measurement of RANKL in human samples supports research into neurological disorders, autoimmune diseases, and bone-related pathologies. This panel enables sensitive and specific quantification of RANKL, facilitating translational studies and therapeutic monitoring in neuroscience and immunology.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Quantify RANKL in human serum, plasma, or tissue culture supernatant samples.
Analyte included: RANKL (Receptor Activator of Nuclear Factor Kappa-B Ligand)
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Analyte included: RANKL (Receptor Activator of Nuclear Factor Kappa-B Ligand)
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
Features:
- Singleplex magnetic bead-based assay for targeted RANKL quantification
- Utilizes Luminex® xMAP® technology for high-throughput and reproducible results
- Compatible with human serum, plasma, and tissue culture supernatants
- High sensitivity and specificity for low-abundance detection
- Includes all necessary reagents and standards for streamlined workflow
- Verified for precision, reproducibility, and minimal cross-reactivity
- Enables focused analysis of RANKL in bone metabolism and immune signaling research
- Ideal for studies on osteoporosis, arthritis, and cancer-related bone loss
- Reduces sample volume requirements while delivering reliable data
- Saves time and cost compared to traditional ELISA methods
- Supports both basic and translational research in skeletal biology
Legal Information
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
法规信息
新产品
此项目有
Janaina Ramalho et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 34(9), 1574-1584 (2019-07-04)
Bone mineral density (BMD) loss is a known complication of human immunodeficiency virus (HIV) infection and its treatment, particularly with tenofovir disoproxil fumarate (TDF)-containing antiretroviral regimens. Although renal proximal tubular dysfunction and phosphaturia is common with TDF, it is unknown
Panagiota Klentrou et al.
Children (Basel, Switzerland), 8(11) (2021-11-28)
Thirteen female adolescent soccer players (14.3 ± 1.3 years) participated in a cross-over, double-blind trial examining the effects of Greek yogurt (GY) consumption on bone biomarkers during 5 days of intense soccer training. The study took place over two intervention
Joel L Prowting et al.
Frontiers in nutrition, 9, 840973-840973 (2022-05-17)
Dairy products and impact exercise have previously been identified to be independently beneficial for bone mineral properties, however, it is unknown how the combination of these two osteogenic interventions may alter acute bone turnover. Using a randomized crossover design, we
Péter Jávor et al.
International journal of molecular sciences, 23(14) (2022-07-28)
There is growing evidence regarding the role of mitochondrial dysfunction in osteoarthritis (OA) and rheumatoid arthritis (RA). However, quantitative comparison of synovial mitochondrial derangements in these main arthritis forms is missing. A prospective clinical study was conducted on adult patients
Maria H Pham et al.
Journal of tissue engineering, 10, 2041731419828950-2041731419828950 (2019-02-26)
The attachment of implants relies on bone and soft tissue biocompatibility. The aim of this article is to investigate the effect of fluoride-modified metallic titanium (Ti) surfaces (Ti-F) on proliferation and differentiation of human gingival fibroblasts. Human gingival fibroblast cells
相关内容
Multiplex immunoassays, such as MILLIPLEX® multiplex metabolic assays, are critical in metabolic syndrome research because they provide a full picture of the different conditions related to it, like diabetes and obesity, as well as save time and sample volume.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持