AB2299
Anti-NR2E3 Antibody
from rabbit
别名:
Nuclear receptor subfamily 2 group E member 3, Retina-specific nuclear receptor, nuclear receptor subfamily 2, group E, member 3, photoreceptor-specific nuclear receptor
生物来源
rabbit
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
bovine
种属反应性（根据同源性预测）
mouse, human, rat
技术
western blot: suitable
UniProt登记号
运输
wet ice
一般描述
NR2E3 protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
~44 kDa
免疫原
Epitope: Full Length Protein
应用
Anti-NR2E3 Antibody is an antibody against NR2E3 for use in WB.
生化/生理作用
Cat. # AB2299 recognizes NR2E3 protein.
Reactivity with other species has not been determined.
外形
Purified by GST-depletion followed by Protein A
Format: Purified
分析说明
Control
Bovine Retina tissue lysate.
Bovine Retina tissue lysate.
Western Blot:
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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储存分类代码
10-13 - German Storage Class 10 to 13
法规信息
新产品
此项目有
Sarah Naessens et al.
Genes, 10(5) (2019-05-15)
The recurrent missense variant in Nuclear Receptor Subfamily 2 Group E Member 3 (NR2E3), c.166G>A, p.(Gly56Arg) or G56R, underlies 1%-2% of cases with autosomal dominant retinitis pigmentosa (adRP), a frequent, genetically heterogeneous inherited retinal disease (IRD). The mutant NR2E3 protein
N Zabouri et al.
The Journal of comparative neurology, 519(7), 1258-1280 (2011-04-01)
Cannabinoid receptor type 1 (CB1R) participates in developmental processes in the central nervous system (CNS). The rodent retina represents an interesting and valuable model for studying CNS development, because it contains well-identified cell types with clearly established and distinct developmental
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