AB2299
Anti-NR2E3 Antibody
from rabbit
别名:
Nuclear receptor subfamily 2 group E member 3, Retina-specific nuclear receptor, nuclear receptor subfamily 2, group E, member 3, photoreceptor-specific nuclear receptor
biological source
rabbit
antibody product type
primary antibodies
clone
polyclonal
species reactivity
bovine
species reactivity (predicted by homology)
mouse, human, rat
technique(s)
western blot: suitable
UniProt accession no.
shipped in
wet ice
General description
NR2E3 protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
~44 kDa
Immunogen
Epitope: Full Length Protein
Application
Anti-NR2E3 Antibody is an antibody against NR2E3 for use in WB.
Biochem/physiol Actions
Cat. # AB2299 recognizes NR2E3 protein.
Reactivity with other species has not been determined.
Physical form
Format: Purified
Purified by GST-depletion followed by Protein A
Analysis Note
Control
Bovine Retina tissue lysate.
Bovine Retina tissue lysate.
Western Blot:
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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存储类别
10-13 - German Storage Class 10 to 13
法规信息
新产品
此项目有
Sarah Naessens et al.
Genes, 10(5) (2019-05-15)
The recurrent missense variant in Nuclear Receptor Subfamily 2 Group E Member 3 (NR2E3), c.166G>A, p.(Gly56Arg) or G56R, underlies 1%-2% of cases with autosomal dominant retinitis pigmentosa (adRP), a frequent, genetically heterogeneous inherited retinal disease (IRD). The mutant NR2E3 protein
N Zabouri et al.
The Journal of comparative neurology, 519(7), 1258-1280 (2011-04-01)
Cannabinoid receptor type 1 (CB1R) participates in developmental processes in the central nervous system (CNS). The rodent retina represents an interesting and valuable model for studying CNS development, because it contains well-identified cell types with clearly established and distinct developmental
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