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Merck
CN

AB5372

Sigma-Aldrich

Anti-Trk B Antibody, pain, a.a. 54-67 rTrkB

serum, Chemicon®

别名:

BDNF/NT-3 Growth Factors Receptor, Tyrosine Kinase Receptor B

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关于此项目

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

serum

抗体产品类型

primary antibodies

克隆

polyclonal

种属反应性

rat, human

制造商/商品名称

Chemicon®

技术

immunohistochemistry: suitable
western blot: suitable

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

human ... NTRK2(4915)

免疫原

A synthetic peptide from rat trkB
Epitope: a.a. 54-67 rtrkB

应用

Anti-Trk B Antibody, pain, a.a. 54-67 rTrkB detects level of Trk B & has been published & validated for use in IH & WB.
Immunohistochemistry: 1:2,000-1:3,000. The antibody reacts well with tissue from the rat spinal cord.
Immunoblotting: 1:1,000-1:1,500 on rat membrane preparations. The antibody should be
evaluated for use in Western blot by the end user. Its utility will be dependant on the level of
the protein expressed in the tissues or cells being tested.
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins

生化/生理作用

TrkB. The sequence used for the immunogen was chosen to avoid cross reactivity with trkA or trkC.

外形

Rabbit serum. Lyophilized. Contains no preservative. Reconstitute with 50 μL of sterile distilled water. Centrifuge if necessary to remove any residue.

制备说明

Maintain lyophilized material at -20°C to -70°C for up to 6 months after date of receipt. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Amy A Robinson et al.
GeroScience, 40(1), 31-47 (2018-01-23)
Mammalian aging is associated with decline in cognitive functions. Studies searching for a cause of cognitive aging initially focused on neuronal loss but quantitative investigations of rat, monkey, and human brain using stereology demonstrated that in normal aging, unlike in
Laurens W J Bosman et al.
Brain cell biology, 35(1), 87-101 (2007-10-18)
The receptor tyrosine kinase TrkB and its ligands, brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5), are critically important for growth, survival and activity-dependent synaptic strengthening in the central nervous system. These TrkB-mediated actions occur in a highly cell-type specific manner.
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