MAB1581
Anti-Aggrecan Antibody
CHEMICON®, mouse monoclonal, Cat-315
别名:
CSPG
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关于此项目
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
Cat-315, monoclonal
Species reactivity:
feline, rat
Application:
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Technique(s):
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Citations:
27
Uniprot accession no.:
产品名称
Anti-Chondroitin Sulfate Proteoglycan Antibody, Core Protein Epitope, clone Cat-315, ascites fluid, clone Cat-315, Chemicon®
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
Cat-315, monoclonal
species reactivity
feline, rat
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgM
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ACAN(176)
Biochem/physiol Actions
Chondroitin sulfate proteoglycan (CSPG), protein core epitope
Application
This Anti-Chondroitin Sulfate Proteoglycan Antibody, Core Protein Epitope, clone Cat-315 is validated for use in IP, WB, IC, IH for the detection of Chondroitin Sulfate Proteoglycan.
Immunohistochemistry: 1:2,000 on 4% paraformaldehyde fixed frozen tissue.
Immunocytochemistry: 1:500 on primary cultures of neurons.
Immunoblot: 1:5,000 recognizes a band at 680 kDa.
Immunoprecipitation.
Optimal working dilutions must be determined by the end user.
Immunocytochemistry: 1:500 on primary cultures of neurons.
Immunoblot: 1:5,000 recognizes a band at 680 kDa.
Immunoprecipitation.
Optimal working dilutions must be determined by the end user.
Immunogen
Epitope: Core Protein Epitope
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Paulette A McRae et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(20), 5405-5413 (2007-05-18)
An important role for the neural extracellular matrix in modulating cortical activity-dependent synaptic plasticity has been established by a number of recent studies. However, identification of the critical molecular components of the neural matrix that mediate these processes is far
Eleanor Grant et al.
Cerebral cortex (New York, N.Y. : 1991), 26(3), 1336-1348 (2016-01-09)
Corticothalamic projection systems arise from 2 main cortical layers. Layer V neurons project exclusively to higher-order thalamic nuclei, while layer VIa fibers project to both first-order and higher-order thalamic nuclei. During early postnatal development, layer VIa and VIb fibers accumulate
Claudia Loebel et al.
Advanced functional materials, 30(44) (2021-07-03)
Hydrogels are engineered with biochemical and biophysical signals to recreate aspects of the native microenvironment and to control cellular functions such as differentiation and matrix deposition. This deposited matrix accumulates within the pericellular space and likely affects the interactions between
Shinji Miyata et al.
Frontiers in integrative neuroscience, 12, 3-3 (2018-02-20)
Aggrecan, a chondroitin sulfate (CS) proteoglycan, forms lattice-like extracellular matrix structures called perineuronal nets (PNNs). Neocortical PNNs primarily ensheath parvalbumin-expressing inhibitory neurons (parvalbumin, PV cells) late in brain development. Emerging evidence indicates that PNNs promote the maturation of PV cells
Andrew Nathaniel Stewart et al.
Restorative neurology and neuroscience, 35(4), 395-411 (2017-06-10)
Utilizing genetic overexpression of trophic molecules in cell populations has been a promising strategy to develop cell replacement therapies for spinal cord injury (SCI). Over-expressing the chemokine, stromal derived factor-1 (SDF-1α), which has chemotactic effects on many cells of the
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