产品名称
Anti-Chondroitin Sulfate Proteoglycan Antibody, Core Protein Epitope, clone Cat-315, ascites fluid, clone Cat-315, Chemicon®
生物来源
mouse
质量水平
抗体形式
ascites fluid
抗体产品类型
primary antibodies
克隆
Cat-315, monoclonal
种属反应性
feline, rat
制造商/商品名称
Chemicon®
技术
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgM
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... ACAN(176)
免疫原
Epitope: Core Protein Epitope
应用
Immunohistochemistry: 1:2,000 on 4% paraformaldehyde fixed frozen tissue.
Immunocytochemistry: 1:500 on primary cultures of neurons.
Immunoblot: 1:5,000 recognizes a band at 680 kDa.
Immunoprecipitation.
Optimal working dilutions must be determined by the end user.
Immunocytochemistry: 1:500 on primary cultures of neurons.
Immunoblot: 1:5,000 recognizes a band at 680 kDa.
Immunoprecipitation.
Optimal working dilutions must be determined by the end user.
This Anti-Chondroitin Sulfate Proteoglycan Antibody, Core Protein Epitope, clone Cat-315 is validated for use in IP, WB, IC, IH for the detection of Chondroitin Sulfate Proteoglycan.
生化/生理作用
Chondroitin sulfate proteoglycan (CSPG), protein core epitope
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Andrew Nathaniel Stewart et al.
Restorative neurology and neuroscience, 35(4), 395-411 (2017-06-10)
Utilizing genetic overexpression of trophic molecules in cell populations has been a promising strategy to develop cell replacement therapies for spinal cord injury (SCI). Over-expressing the chemokine, stromal derived factor-1 (SDF-1α), which has chemotactic effects on many cells of the
Claudia Loebel et al.
Advanced functional materials, 30(44) (2021-07-03)
Hydrogels are engineered with biochemical and biophysical signals to recreate aspects of the native microenvironment and to control cellular functions such as differentiation and matrix deposition. This deposited matrix accumulates within the pericellular space and likely affects the interactions between
Paulette A McRae et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(20), 5405-5413 (2007-05-18)
An important role for the neural extracellular matrix in modulating cortical activity-dependent synaptic plasticity has been established by a number of recent studies. However, identification of the critical molecular components of the neural matrix that mediate these processes is far
Shinji Miyata et al.
Frontiers in integrative neuroscience, 12, 3-3 (2018-02-20)
Aggrecan, a chondroitin sulfate (CS) proteoglycan, forms lattice-like extracellular matrix structures called perineuronal nets (PNNs). Neocortical PNNs primarily ensheath parvalbumin-expressing inhibitory neurons (parvalbumin, PV cells) late in brain development. Emerging evidence indicates that PNNs promote the maturation of PV cells
Alicia L Hawthorne et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 30(2), 420-430 (2010-01-15)
Embryonic CNS neurons can migrate from the ventricular zone to their final destination by radial glial-guided locomotion. Another less appreciated mechanism is somal translocation, where the young neuron maintains its primitive ventricular and pial processes, through which the cell body
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