Product Name
Anti-Vimentin Antibody, clone LN-6, culture supernatant, clone LN-6, Chemicon®
生物来源
mouse
抗体形式
culture supernatant
抗体产品类型
primary antibodies
克隆
LN-6, monoclonal
分子量
calculated mol wt 53.65 kDa
observed mol wt ~N/A kDa
种属反应性
human, mouse
包装
antibody small pack of 1
制造商/商品名称
Chemicon®
技术
immunohistochemistry: suitable (paraffin)
同位素/亚型
IgM
表位序列
Unknown
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
-10 to -25°C
靶向翻译后修饰
unmodified
基因信息
human ... VIM(7431)
一般描述
Vimentin is a class III intermediate filament protein (homopolymers) found in various non-epithelial cells including mesenchymal cells and fibroblasts. In many cells of mesenchymal origin, it is one of the most prominent phosphoproteins, especially during cell division when enhanced phosphorylation of vimentin corresponds with the reorganization of vimentin filaments.
57-60 kDa
免疫原
Nuclei from adult human thymic biopsy specimens.
应用
Anti-Vimentin Antibody, clone LN-6 detects level of Vimentin & has been published & validated for use in IH(P).
Immunohistochemistry on B5 fixed, paraffin embedded tissue sections.
生化/生理作用
Reacts with human mesenchymal cells and derived sarcomas. Reacts with an epitope of the cytoskeletal protein vimentin but unlike other vimentin antibodies, does not react with human lymphoid cells or derived malignancies. Reactive with endothelium, muscle, fibroblasts, melanocytes, peripheral nerve, sertoli cells, kidney mesangial cells and tubules, osteoblasts and periosteum, non-hematopoietic tumors of mesenchymal origin (all sarcomas), meningiomas and melanomas.
外形
Liquid tissue culture supernatant containing 0.02% sodium azide.
制备说明
Please refer to guidance on suggested starting dilutions and/or titers per application and sample type.
Store at -10°C to -25°C. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
分析说明
Control
Hyperplastic lymph nodes.
Hyperplastic lymph nodes.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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