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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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Product Name

Anti-Vimentin Antibody, clone LN-6, culture supernatant, clone LN-6, Chemicon®

生物来源

mouse

质量水平

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

LN-6, monoclonal

分子量

calculated mol wt 53.65 kDa
observed mol wt ~N/A kDa

种属反应性

human, mouse

包装

antibody small pack of 1

制造商/商品名称

Chemicon®

技术

immunohistochemistry: suitable (paraffin)

同位素/亚型

IgM

表位序列

Unknown

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

-10 to -25°C

靶向翻译后修饰

unmodified

基因信息

human ... VIM(7431)

一般描述

Vimentin is a class III intermediate filament protein (homopolymers) found in various non-epithelial cells including mesenchymal cells and fibroblasts. In many cells of mesenchymal origin, it is one of the most prominent phosphoproteins, especially during cell division when enhanced phosphorylation of vimentin corresponds with the reorganization of vimentin filaments.

特异性

Reacts with human mesenchymal cells and derived sarcomas. Reacts with an epitope of the cytoskeletal protein vimentin but unlike other vimentin antibodies, does not react with human lymphoid cells or derived malignancies. Reactive with endothelium, muscle, fibroblasts, melanocytes, peripheral nerve, sertoli cells, kidney mesangial cells and tubules, osteoblasts and periosteum, non-hematopoietic tumors of mesenchymal origin (all sarcomas), meningiomas and melanomas.

免疫原

Nuclei from adult human thymic biopsy specimens.

应用

Anti-Vimentin Antibody, clone LN-6 detects level of Vimentin & has been published & validated for use in IH(P).
Immunohistochemistry on B5 fixed, paraffin embedded tissue sections.

目标描述

57-60 kDa

外形

Liquid tissue culture supernatant containing 0.02% sodium azide.

重悬

Please refer to guidance on suggested starting dilutions and/or titers per application and sample type.

储存及稳定性

Store at -10°C to -25°C. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析说明

Control
Hyperplastic lymph nodes.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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