生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
ascites fluid
抗体产品类型
primary antibodies
克隆
monoclonal
种属反应性
mouse, human
制造商/商品名称
Chemicon®
技术
ELISA: suitable
immunocytochemistry: suitable
western blot: suitable
同位素/亚型
IgG2b
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... TRIM28(10155)
免疫原
Recombinant protein from mouse TIF1b.
应用
Anti-TIF1 beta Antibody is a Mouse Monoclonal Antibody for detection of Transcriptional Intermediary Factor 1 also known as TIF1 beta & has been validated in ELISA, WB, ICC.
Western blot: 1:500-1:5,000
Immunocytochemistry: 1:500-1:5,000
ELISA: 1:500-1:5,000
Optimal working dilutions must be determined by the end user.
Immunocytochemistry: 1:500-1:5,000
ELISA: 1:500-1:5,000
Optimal working dilutions must be determined by the end user.
生化/生理作用
Recognizes transcriptional intermediary factor 1beta (TIF1beta). The epitope is localized between amino acids 123-834 of mouse TIF1beta. No cross reactivity with TIF1alpha.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Andrea Coluccio et al.
Epigenetics & chromatin, 11(1), 7-7 (2018-02-28)
The KZFP/KAP1 (KRAB zinc finger proteins/KRAB-associated protein 1) system plays a central role in repressing transposable elements (TEs) and maintaining parent-of-origin DNA methylation at imprinting control regions (ICRs) during the wave of genome-wide reprogramming that precedes implantation. In naïve murine
Nozomi Takahashi et al.
Genes & development, 33(1-2), 49-54 (2019-01-04)
Genomic imprinting is an epigenetic process regulated by germline-derived DNA methylation, causing parental origin-specific monoallelic gene expression. Zinc finger protein 57 (ZFP57) is critical for maintenance of this epigenetic memory during post-fertilization reprogramming, yet incomplete penetrance of ZFP57 mutations in
Maëva Devoucoux et al.
Molecular & cellular proteomics : MCP, 21(7), 100253-100253 (2022-06-01)
MRG15/MORF4L1 is a highly conserved protein in eukaryotes that contains a chromodomain (CHD) recognizing methylation of lysine 36 on histone H3 (H3K36me3) in chromatin. Intriguingly, it has been reported in the literature to interact with several different factors involved in
Helen M Rowe et al.
Development (Cambridge, England), 140(3), 519-529 (2013-01-08)
Endogenous retroviruses (ERVs) undergo de novo DNA methylation during the first few days of mammalian embryogenesis, although the factors that control the targeting of this process are largely unknown. We asked whether KAP1 (KRAB-associated protein 1) is involved in this
Christopher Hc Tie et al.
EMBO reports, 19(10) (2018-08-01)
Endogenous retroviruses (ERVs) have accumulated in vertebrate genomes and contribute to the complexity of gene regulation. KAP1 represses ERVs during development by its recruitment to their repetitive sequences through KRAB zinc-finger proteins (KZNFs), but little is known about the regulation
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