产品名称
抗-SV40 Large T Antigen抗体，克隆PAb416, clone PAb416, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
PAb416, monoclonal
species reactivity
SV40-infected cells
technique(s)
immunocytochemistry: suitable
western blot: suitable
isotype
IgG2aκ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Biochem/physiol Actions
该抗体识别SV40的大T抗原。
Analysis Note
对照
Cos-1细胞裂解物
Cos-1细胞裂解物
通过蛋白质印迹法在Cos-1细胞裂解物中进行评估。
蛋白质印迹分析：1 µg/mL的该抗体在10 µg Cos-1细胞裂解物中检测到SV40大T抗原。
蛋白质印迹分析：1 µg/mL的该抗体在10 µg Cos-1细胞裂解物中检测到SV40大T抗原。
Application
免疫细胞化学分析：一个来自独立实验室的代表性批次在ICC中检测到SV40大T抗原（Sabatier，J.，et al.（2005）.58(4):429-431.; Del Valle, L., et al. (2004).J Virol.78（7）:3462-3469.）。
抗SV40大T抗原抗体，克隆PAb416是抗SV40大T抗原的抗体，用于蛋白质印迹、ICC。
研究子类别
免疫球蛋白 & 免疫学
免疫球蛋白 & 免疫学
研究类别
炎症 & 免疫学
炎症 & 免疫学
Disclaimer
除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
General description
猿猴病毒（SV40）大T和小T抗原均由SV40基因组的早期区域编码。大的T抗原结合DNA，并与53,000道尔顿的细胞蛋白p53形成复合物，p53是裂解生长过程中启动病毒DNA复制所必需的。此外，大T抗原与DNA聚合酶和转录因子AP-2结合，并与视网膜母细胞瘤易感基因的P105产物形成特异性复合物。
观测分子量〜82 kDa
Immunogen
纯化的SV40大T抗原
表位：SV40大T抗原
Other Notes
浓度：关于批次特定浓度请参见检验报告。
Physical form
形式：纯化
纯化的小鼠单克隆IgG2aκ，溶于含0.1 M Tris-甘氨酸（pH 7.4）、150 mM NaCl和0.05％叠氮化钠的缓冲液中。
纯化蛋白G
Preparation Note
自接收之日起，在2-8°C下可稳定保存1年。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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