跳转至内容
Merck
CN

OP133

Anti-IKKα Mouse mAb (14A231)

liquid, clone 14A231, Calbiochem®

登录 查看组织和合同定价。

选择尺寸


关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

Anti-IKKα Mouse mAb (14A231), liquid, clone 14A231, Calbiochem®

biological source

mouse

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

14A231, monoclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

monkey, human, mouse

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

dilution

(Immunoblotting (1-2 µg/mL, chemiluminescence))

isotype

IgG1

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... CHUK(1147)

General description

Recognizes the ~85 kDa IKKα protein in Daudi cells.
This Anti-IKKα Mouse mAb (14A231) is validated for use in Immunoblotting for the detection of IKKα.
Immunoaffinity purified mouse monoclonal antibody. Recognizes the ~85 kDa IKKα protein.

Immunogen

Human
a recombinant protein consisting of full-length human IKKα/IKK1 fused to a His•Tag sequence

Analysis Note

Positive Control
Daudi cells

Application


Immunoblotting (1-2 g/ml, chemiluminescence)

Disclaimer

Toxicity: Standard Handling (A)

Other Notes

Antibody should be titrated for optimal results in individual systems.
Zandi, E., et al. 1998 Science281, 1360.
Didonato, J.A., et al. 1997 Nature388, 548.
Lee, F.S., et al. 1997 Cell88, 213.
Mercurio, F., et al. 1997 Science278, 860.
Regnier, C.H., et al. M. 1997 Cell90, 373.
Verma, I. and Stevenson, J.K. 1997 Proc. Nat. Acad. Sci. USA94, 11758.
Verma, I.M., et al. 1995 Genes. Dev.9, 2723.

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In PBS, 0.2% gelatin, pH 7.4.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

未找到合适的产品?  

试试我们的产品选型工具.

存储类别

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品
此项目有

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Faiyaz Ahmad et al.
Scientific reports, 6, 28056-28056 (2016-06-21)
Activation of inflammation in white adipose tissue (WAT), includes infiltration/expansion of WAT macrophages, contributes pathogenesis of obesity, insulin resistance, and metabolic syndrome. The inflammasome comprises an intracellular sensor (NLR), caspase-1 and the adaptor ASC. Inflammasome activation leads to maturation of
Michael L Kamradt et al.
Cell death & disease, 12(3), 271-271 (2021-03-17)
Cancers, including glioblastoma multiforme (GBM), undergo coordinated reprogramming of metabolic pathways that control glycolysis and oxidative phosphorylation (OXPHOS) to promote tumor growth in diverse tumor microenvironments. Adaptation to limited nutrient availability in the microenvironment is associated with remodeling of mitochondrial
Cristina Aguilera et al.
Proceedings of the National Academy of Sciences of the United States of America, 101(47), 16537-16542 (2004-11-13)
The NF-kappaB pathway plays a pivotal role in proliferation, differentiation, apoptosis, and immune responses in mammals. The NF-kappaB inhibitor, IkappaB, has classically been characterized for its ability to sequester NF-kappaB transcription factors in the cytoplasm. Nevertheless, a nuclear fraction of
Justin N Keeney et al.
Journal of immunology (Baltimore, Md. : 1950), 210(8), 1123-1133 (2023-03-08)
NF-κB-inducing kinase (NIK), which is essential for the activation of the noncanonical NF-κB pathway, regulates diverse processes in immunity, development, and disease. Although recent studies have elucidated important functions of NIK in adaptive immune cells and cancer cell metabolism, the
Lindsay Bennett et al.
International journal of cancer, 140(7), 1633-1644 (2016-12-23)
The aim of our study was to examine the relationship between tumour IKKα expression and breast cancer recurrence and survival. Immunohistochemistry was employed in a discovery and a validation tissue microarray to assess the association of tumour IKKα expression and

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持