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PC150

Anti-β-Amyloid (1-42) Rabbit pAb

Name: Anti-β-Amyloid (1-42) Rabbit pAb
Brand: MM

liquid, Calbiochem^®

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关于此项目

NACRES:

NA.41

UNSPSC Code:

12352203

Clone:

polyclonal

Species reactivity:

human

Application:

—

Citations:

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属性

biological source

rabbit

Quality Segment

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

does not contain

preservative

species reactivity

human

packaging

antibody small pack of 25 μg

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(Dot Blot (0.1-0.5 µg/mL)
ELISA (0.1-0.5 µg/mL)
Radioimmunoassay (0.5 µg/mL))

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... APP(351)

说明

General description

Rabbit polyclonal antibody adsorbed against Aβ_1-40 and Aβ_1-43, followed by immunoaffinity purification. Recognizes specifically β-amyloid peptide (1-42).

Recognizes specifically β-amyloid peptide (1-42). Does not cross-react with β-amyloid peptide (1-40) or β-amyloid peptide (1-43).

Antibody Target Gene Symbol: APP
Target Synonym: AAA, AD1, Adap, AL024401, Amyloid precursor, Amyloidogenic glycoprotein, APP isoform 1, APPI, appican, CTFgamma, CVAP, E030013M08RIK, Nexin II, P3, PN2, PreA4, PROTEASE NEXIN2
Entrez Gene Name: amyloid beta (A4) precursor protein
Hu Entrez ID: 351 (Related Antibodies: 171610, PC729,PC152, PC151, PC149, NE1012, 171609, 171608, 171607, 171606, 171605, 171604, 171603, 171598, 171537)
Mu Entrez ID: 11820
Rat Entrez ID: 54226

This Anti-β-Amyloid (1-42) Rabbit pAb is validated for use in Dot Blot, ELISA, Radioimmunoassay for the detection of β-Amyloid (1-42).

Immunogen

Human

a synthetic peptide corresponding to amino acids from a C-terminal fragment of human β-amyloid peptide (1-42)

Application

Dot Blot (0.1-0.5 µg/ml)

ELISA (0.1-0.5 µg/ml)

Radioimmunoassay (0.5 µg/ml)

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In phosphate buffer, pH 7.4.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Savage, M.J., et al. 1998. J. Neurosci.15, 1743.
Borchelt, D.R., et al. 1997. Neuron19, 939.
Citron, M., et al. 1997. Nature Med.3, 67.
Hardy, J. 1997. Trends in Neurosci.20, 154.
Solomon, B., et al. 1997. Proc. Natl. Acad. Sci. USA94, 4109.
Duff, K., et al. 1996. Nature383, 710.
Iwatsubo, T., et al. 1994. Neuron13, 45.
Suzuki, N., et al. 1994. Science264, 133.

This antibody is specific for β-amyloid peptide [1-42] and shows no reactivity to β-amyloid peptide [1-40] or β-amyloid peptide [1-43]. This antibody is recommended for use in the quantitative determination of β-amyloid peptide [1-42]. The sensitivity level for sandwich ELISA is 15-25 pg. Antibody should be titrated for optimal results in individual systems.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c