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Merck
CN

00020590

1,8-桉叶素

primary reference standard

别名:

桉树脑, 1,3,3-三甲基-2-氧杂二环[2.2.2]辛烷, 1,8-桉叶素, 1,8-环氧对孟烷

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经验公式(希尔记法):
C10H18O
化学文摘社编号:
分子量:
154.25
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-431-5
Beilstein/REAXYS Number:
105109
MDL number:
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InChI

1S/C10H18O/c1-9(2)8-4-6-10(3,11-9)7-5-8/h8H,4-7H2,1-3H3/t8-,10+

InChI key

WEEGYLXZBRQIMU-WAAGHKOSSA-N

SMILES string

C[C@]12CC[C@H](CC1)C(C)(C)O2

grade

primary reference standard

form

liquid

CofA

certificate is enclosed in each package

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

refractive index

n20/D 1.457 (lit.)

bp

176-177 °C (lit.)

mp

1-2 °C (lit.)

density

0.921 g/mL at 25 °C (lit.)

storage temp.

−20°C

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General description

1,8-桉叶素是精油的主要成分。它是一种萜烯氧化物。它可用作经皮渗透促进剂、皮肤浴中的皮肤兴奋剂,并用于治疗支气管炎、鼻窦炎和风湿病。它具有解充血和镇咳作用。
由 HWI pharma services GmbH 生产并鉴定。
通过定量 NMR 测得的准确含量可参见证书。

Application

1,8-桉叶素可用于 GC-MS 定量分析丹参挥发性和半挥发性成分。
草药药品分析中的对照标准

Other Notes

该化合物常见于下列属的植物:蓍属、当归属、桂属、姜黄属、桉属、薄荷属、鼠尾草属、百里香属、缬草属、姜属

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.

pictograms

FlameExclamation mark

signalword

Warning

hcodes

Hazard Classifications

Flam. Liq. 3 - Skin Sens. 1

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

125.6 °F - closed cup

flash_point_c

52 °C - closed cup

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Capillary gas chromatography-mass spectrometry of volatile and semi-volatile compounds of Salvia officinalis.
Radulescu V, Chiliment S, Oprea E.
Journal of Chromatography A, 1027(1-2), 121-126 (2004)
Antiinflammatory and antinociceptive effects of 1,8-cineole a terpenoid oxide present in many plant essential oils.
Santos FA, Rao VS.
Phytotherapy Research, 14(4), 240-244 (2000)
Hee-jin Jun et al.
Bioorganic & medicinal chemistry letters, 23(2), 579-583 (2012-12-19)
We investigated the effect of cineole on the expression of genes related to reverse cholesterol transport and hepatic fatty acid metabolism. Cineole, a small aroma compound in teas and herbs, significantly stimulated the transactivation of liver X receptor modulator (LXR)-α
Zerihun A Demissie et al.
Plant molecular biology, 79(4-5), 393-411 (2012-05-18)
Several members of the genus Lavandula produce valuable essential oils (EOs) that are primarily constituted of the low molecular weight isoprenoids, particularly monoterpenes. We isolated over 8,000 ESTs from the glandular trichomes of L. x intermedia flowers (where bulk of
Lisa A Shipley et al.
Journal of chemical ecology, 38(9), 1178-1189 (2012-10-12)
Pygmy rabbits (Brachylagus idahoensis) are one of only three vertebrates that subsist virtually exclusively on sagebrush (Artemisia spp.), which contains high levels of monoterpenes that can be toxic. We examined the mechanisms used by specialist pygmy rabbits to eliminate 1,8-cineole

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