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线性分子式:
(HO)2C6H3CO2H
化学文摘社编号:
分子量:
154.12
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
202-760-0
Beilstein/REAXYS Number:
1448841
MDL number:
产品名称
原儿茶酸, primary reference standard
InChI key
YQUVCSBJEUQKSH-UHFFFAOYSA-N
InChI
1S/C7H6O4/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,8-9H,(H,10,11)
SMILES string
OC(=O)c1ccc(O)c(O)c1
grade
primary reference standard
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
HWI
mp
197-200 °C (dec.) (lit.)
application(s)
food and beverages
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Application
草药药品分析中的参比标准品
Biochem/physiol Actions
几个致癌作用的动物模型中的化学防癌剂。在后启动阶段阻断细胞增殖。
General description
原儿茶酸属于多酚类化合物，一般可从玫瑰茄干花中分离得到。它可以作为一种潜在的具有抗癌作用的候选药物，参与抑制人早幼粒白血病 HL-60 细胞的生长。
由HWI制药服务股份有限公司生产和认证。
通过定量NMR获得的确切含量可在证书上找到。
通过定量NMR获得的确切含量可在证书上找到。
Other Notes
此化合物通常存在于以下属植物中： 大蒜 葛缕子 肉桂 姜黄 银杏 葎草 香蜂草 茴香 百里香
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
T H Tseng et al.
Biochemical pharmacology, 60(3), 307-315 (2000-06-17)
Hibiscus protocatechuic acid (PCA), a phenolic compound isolated from the dried flower of Hibiscus sabdariffa L. (Malvaceae), demonstrated antioxidant and antitumor promotion effects in our previous study. In the present study, Hibiscus PCA was found to inhibit the survival of
In vivo protective effect of protocatechuic acid on tert-butyl hydroperoxide-induced rat hepatotoxicity
Liu C-L, et al.
Food And Chemical Toxicology, 40, 635-641 (2002)
Saravanan Palani et al.
eLife, 10 (2021-07-17)
Actin filaments are central to numerous biological processes in all domains of life. Driven by the interplay with molecular motors, actin binding and actin modulating proteins, the actin cytoskeleton exhibits a variety of geometries. This includes structures with a curved
Kaarjel K Narayanasamy et al.
Frontiers in synaptic neuroscience, 13, 671288-671288 (2021-07-06)
The development of super-resolution microscopy (SRM) has widened our understanding of biomolecular structure and function in biological materials. Imaging multiple targets within a single area would elucidate their spatial localization relative to the cell matrix and neighboring biomolecules, revealing multi-protein
Dongliang Wang et al.
Circulation research, 111(8), 967-981 (2012-07-24)
We and others have demonstrated that anthocyanins have antiatherogenic capability. Because intact anthocyanins are absorbed very poorly, the low level of circulating parent anthocyanins may not fully account for their beneficial effect. We found recently that protocatechuic acid (PCA), a
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