03930590
原儿茶酸
primary reference standard
别名:
3,4-二羟基苯甲酸, 原儿茶酸
等级
primary reference standard
保质期
limited shelf life, expiry date on the label
制造商/商品名称
HWI
mp
197-200 °C (dec.) (lit.)
应用
food and beverages
SMILES字符串
OC(=O)c1ccc(O)c(O)c1
InChI
1S/C7H6O4/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,8-9H,(H,10,11)
InChI key
YQUVCSBJEUQKSH-UHFFFAOYSA-N
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一般描述
原儿茶酸属于多酚类化合物,一般可从玫瑰茄干花中分离得到。它可以作为一种潜在的具有抗癌作用的候选药物,参与抑制人早幼粒白血病 HL-60 细胞的生长。
由HWI制药服务股份有限公司生产和认证。
通过定量NMR获得的确切含量可在证书上找到。
通过定量NMR获得的确切含量可在证书上找到。
应用
草药药品分析中的参比标准品
生化/生理作用
几个致癌作用的动物模型中的化学防癌剂。在后启动阶段阻断细胞增殖。
其他说明
此化合物通常存在于以下属植物中: 大蒜 葛缕子 肉桂 姜黄 银杏 葎草 香蜂草 茴香 百里香
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
T H Tseng et al.
Biochemical pharmacology, 60(3), 307-315 (2000-06-17)
Hibiscus protocatechuic acid (PCA), a phenolic compound isolated from the dried flower of Hibiscus sabdariffa L. (Malvaceae), demonstrated antioxidant and antitumor promotion effects in our previous study. In the present study, Hibiscus PCA was found to inhibit the survival of
In vivo protective effect of protocatechuic acid on tert-butyl hydroperoxide-induced rat hepatotoxicity
Liu C-L, et al.
Food And Chemical Toxicology, 40, 635-641 (2002)
Saravanan Palani et al.
eLife, 10 (2021-07-17)
Actin filaments are central to numerous biological processes in all domains of life. Driven by the interplay with molecular motors, actin binding and actin modulating proteins, the actin cytoskeleton exhibits a variety of geometries. This includes structures with a curved
Qing-Han Gao et al.
Journal of agricultural and food chemistry, 60(38), 9642-9648 (2012-09-11)
This study investigated the changes in sugars, organic acids, α-tocopherol, β-carotene, phenolic profiles, total phenolic content (TPC), and antioxidant capacity of jujube fruits after four drying treatments (sun-, oven-, microwave- and freeze-drying). Sugar, organic acid, phenolic compounds, α-tocopherol, and β-carotene
J Kristinsson et al.
Pharmacology & toxicology, 74(3), 174-180 (1994-03-01)
The urinary metabolites of orally administered mebeverine hydrochloride (270 mg) were studied in five healthy volunteers with the aid of gas chromatography/mass spectrometry. Mebeverine, which is an ester of veratric acid and 4-(ethyl-[2-(4-methoxyphenyl)-1-methylethyl]amino)butan-1-ol, was completely hydrolysed to the corresponding acid
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