07097
Aminobenzyl-EDTA
≥90% (CHN)
别名:
1-(4-Aminobenzyl)ethylenediamine-N,N,N′,N′-tetraacetic acid
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关于此项目
经验公式（希尔记法）:
C17H23N3O8
化学文摘社编号:
分子量:
397.38
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352103
MDL number:
Quality Level
assay
≥90% (CHN)
storage temp.
−20°C
SMILES string
Nc1ccc(CC(CN(CC(O)=O)CC(O)=O)N(CC(O)=O)CC(O)=O)cc1
InChI
1S/C17H23N3O8/c18-12-3-1-11(2-4-12)5-13(20(9-16(25)26)10-17(27)28)6-19(7-14(21)22)8-15(23)24/h1-4,13H,5-10,18H2,(H,21,22)(H,23,24)(H,25,26)(H,27,28)
InChI key
RPBJIOJIMOUOIN-UHFFFAOYSA-N
Application
Aminobenzyl-EDTA has been used to develop an ELISA test for the detection of mercury in water. Aminobenzyl-EDTA has also been used in a study to provide a new class of affinity cleaving reagents that can be directed against protein and nucleic acid targets.
Used to incorporate aminobenzyl-EDTA into peptide by reacting with activated carboxylates such as succinimidylester, p-nitrophenylester, and acid chlorides.
Other Notes
Reagent for labeling biomolecules with EDTA
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
A I Song et al.
Bioconjugate chemistry, 8(2), 249-252 (1997-03-01)
A convenient and straightforward synthesis of an amino acid analog, [p-(N-alpha-Fmoc-L-aspartic acid-beta-amido)benzyl]-EDTA tetra-tert-butyl ester, compatible with Fmoc solid phase peptide synthesis strategy is described. This reagent was used to incorporate p-aminobenzyl-EDTA at an internal sequence position in an HIV-1 Tat
M Studer et al.
Bioconjugate chemistry, 3(5), 424-429 (1992-09-01)
Insight into the metabolism of radiolabeled antibodies is important for the design of better radioimaging and therapy agents. To test the effect of linkers that can be cleaved in vivo, we introduced Ala-Leu-Ala-Leu between the antibody Lym-1 and an 111In-labeled
Yi Zhang et al.
Biological trace element research, 144(1-3), 854-864 (2011-03-26)
Immunoassays for heavy metals offer an alternative approach to traditional techniques for detection of mercury. In this study, a mercury-chelate was prepared with 1-(4-aminobenzyl) ethylenediamine-N,N,N',N'-tetraacetic acid (aminobenzyl-EDTA). The resulting complex was linked to keyhole limpet hemocyanin (KLH) or bovine serum
M Studer et al.
Bioconjugate chemistry, 3(5), 420-423 (1992-09-01)
The synthesis of a protected bifunctional analog of ethylenediaminetetraacetic acid (EDTA) is described. The molecule contains an aminobenzyl moiety that allows the easy attachment of the chelating agent to a wide variety of groups. Examples of reaction with the C-termini
Tao Kong et al.
Biological trace element research, 152(1), 117-124 (2013-02-05)
The detection of cadmium ions using enzyme-linked immunosorbent assays (ELISA) has been reported by several research groups. Because cadmium ions are too small to stimulate the immune system, high molecular weight immunogens of cadmium are constructed using bifunctional chelators. At
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 07097-10MG | 04061838647627 |
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