07097
Aminobenzyl-EDTA
≥90% (CHN)
别名:
1-(4-Aminobenzyl)ethylenediamine-N,N,N′,N′-tetraacetic acid
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关于此项目
经验公式（希尔记法）:
C17H23N3O8
化学文摘社编号:
分子量:
397.38
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352103
MDL number:
InChI
1S/C17H23N3O8/c18-12-3-1-11(2-4-12)5-13(20(9-16(25)26)10-17(27)28)6-19(7-14(21)22)8-15(23)24/h1-4,13H,5-10,18H2,(H,21,22)(H,23,24)(H,25,26)(H,27,28)
SMILES string
Nc1ccc(CC(CN(CC(O)=O)CC(O)=O)N(CC(O)=O)CC(O)=O)cc1
InChI key
RPBJIOJIMOUOIN-UHFFFAOYSA-N
assay
≥90% (CHN)
storage temp.
−20°C
Quality Level
Application
Aminobenzyl-EDTA has been used to develop an ELISA test for the detection of mercury in water. Aminobenzyl-EDTA has also been used in a study to provide a new class of affinity cleaving reagents that can be directed against protein and nucleic acid targets.
Used to incorporate aminobenzyl-EDTA into peptide by reacting with activated carboxylates such as succinimidylester, p-nitrophenylester, and acid chlorides.
Other Notes
Reagent for labeling biomolecules with EDTA
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Yi Zhang et al.
Biological trace element research, 144(1-3), 854-864 (2011-03-26)
Immunoassays for heavy metals offer an alternative approach to traditional techniques for detection of mercury. In this study, a mercury-chelate was prepared with 1-(4-aminobenzyl) ethylenediamine-N,N,N',N'-tetraacetic acid (aminobenzyl-EDTA). The resulting complex was linked to keyhole limpet hemocyanin (KLH) or bovine serum
Tao Kong et al.
Biological trace element research, 152(1), 117-124 (2013-02-05)
The detection of cadmium ions using enzyme-linked immunosorbent assays (ELISA) has been reported by several research groups. Because cadmium ions are too small to stimulate the immune system, high molecular weight immunogens of cadmium are constructed using bifunctional chelators. At
A I Song et al.
Bioconjugate chemistry, 8(2), 249-252 (1997-03-01)
A convenient and straightforward synthesis of an amino acid analog, [p-(N-alpha-Fmoc-L-aspartic acid-beta-amido)benzyl]-EDTA tetra-tert-butyl ester, compatible with Fmoc solid phase peptide synthesis strategy is described. This reagent was used to incorporate p-aminobenzyl-EDTA at an internal sequence position in an HIV-1 Tat
M L Thakur et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 29(11), 1817-1825 (1988-11-01)
Ten monoclonal antibodies (MAbs) have been evaluated as agents for selective radiolabeling of human neutrophils (PMNs). Four bifunctional chelating agents (BFCA) have been compared in order to determine the one that gives the best labeling of MAbs with radionuclides. Of
A J Chmura et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(15), 8480-8484 (2001-07-12)
Here we report an approach to the design and production of antibody/ligand pairs, to achieve functional affinity far greater than avidin/biotin. Using fundamental chemical principles, we have developed antibody/ligand pairs that retain the binding specificity of the antibody, but do
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