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Merck
CN

07097

Sigma-Aldrich

Aminobenzyl-EDTA

≥90% (CHN)

别名:

1-(4-Aminobenzyl)ethylenediamine-N,N,N′,N′-tetra­acetic acid

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关于此项目

经验公式(希尔记法):
C17H23N3O8
化学文摘社编号:
分子量:
397.38
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:
NACRES:
NA.25
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质量水平

方案

≥90% (CHN)

储存温度

−20°C

SMILES字符串

Nc1ccc(CC(CN(CC(O)=O)CC(O)=O)N(CC(O)=O)CC(O)=O)cc1

InChI

1S/C17H23N3O8/c18-12-3-1-11(2-4-12)5-13(20(9-16(25)26)10-17(27)28)6-19(7-14(21)22)8-15(23)24/h1-4,13H,5-10,18H2,(H,21,22)(H,23,24)(H,25,26)(H,27,28)

InChI key

RPBJIOJIMOUOIN-UHFFFAOYSA-N

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应用

Aminobenzyl-EDTA has been used to develop an ELISA test for the detection of mercury in water. Aminobenzyl-EDTA has also been used in a study to provide a new class of affinity cleaving reagents that can be directed against protein and nucleic acid targets.
Used to incorporate aminobenzyl-EDTA into peptide by reacting with activated carboxylates such as succinimidylester, p-nitrophenylester, and acid chlorides.

其他说明

Reagent for labeling biomolecules with EDTA

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A I Song et al.
Bioconjugate chemistry, 8(2), 249-252 (1997-03-01)
A convenient and straightforward synthesis of an amino acid analog, [p-(N-alpha-Fmoc-L-aspartic acid-beta-amido)benzyl]-EDTA tetra-tert-butyl ester, compatible with Fmoc solid phase peptide synthesis strategy is described. This reagent was used to incorporate p-aminobenzyl-EDTA at an internal sequence position in an HIV-1 Tat
M Studer et al.
Bioconjugate chemistry, 3(5), 424-429 (1992-09-01)
Insight into the metabolism of radiolabeled antibodies is important for the design of better radioimaging and therapy agents. To test the effect of linkers that can be cleaved in vivo, we introduced Ala-Leu-Ala-Leu between the antibody Lym-1 and an 111In-labeled
Yi Zhang et al.
Biological trace element research, 144(1-3), 854-864 (2011-03-26)
Immunoassays for heavy metals offer an alternative approach to traditional techniques for detection of mercury. In this study, a mercury-chelate was prepared with 1-(4-aminobenzyl) ethylenediamine-N,N,N',N'-tetraacetic acid (aminobenzyl-EDTA). The resulting complex was linked to keyhole limpet hemocyanin (KLH) or bovine serum
M Studer et al.
Bioconjugate chemistry, 3(5), 420-423 (1992-09-01)
The synthesis of a protected bifunctional analog of ethylenediaminetetraacetic acid (EDTA) is described. The molecule contains an aminobenzyl moiety that allows the easy attachment of the chelating agent to a wide variety of groups. Examples of reaction with the C-termini
Tao Kong et al.
Biological trace element research, 152(1), 117-124 (2013-02-05)
The detection of cadmium ions using enzyme-linked immunosorbent assays (ELISA) has been reported by several research groups. Because cadmium ions are too small to stimulate the immune system, high molecular weight immunogens of cadmium are constructed using bifunctional chelators. At

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