产品名称
羽扇豆醇, analytical standard
InChI key
MQYXUWHLBZFQQO-QGTGJCAVSA-N
InChI
1S/C30H50O/c1-19(2)20-11-14-27(5)17-18-29(7)21(25(20)27)9-10-23-28(6)15-13-24(31)26(3,4)22(28)12-16-30(23,29)8/h20-25,31H,1,9-18H2,2-8H3/t20-,21+,22-,23+,24-,25+,27+,28-,29+,30+/m0/s1
SMILES string
[H]C12CCC3C4(C)CCC(O)C(C)(C)[C@]4([H])CCC3(C)[C@]1(C)CCC5(C)CC[C@H](C(C)=C)[C@]25[H]
grade
analytical standard
assay
≥90.0% (GC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
storage temp.
2-8°C
Quality Level
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Application
It was used as reference standard in method development and validation of lupeol from Vernonia Cinerea using HPLC method.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Lupeol is a novel anti-cancer and anti-inflammatory dietary triterpene. They help in stabilizing phospholipid bilayers in plant cell membranes. In general, this group contains 28-29 carbons along with carbon-carbon double bonds, usually one in the sterol nucleus and at times a second in the alkyl side chain.
Other Notes
This compound is commonly found in plants of the genus: glycyrrhiza sambucus
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Ardiansyah et al.
Bioscience, biotechnology, and biochemistry, 76(1), 183-185 (2012-01-11)
Supplementation with lupeol (0.67 g·kg(-1)) of the AIN-93M-based diet fed for 7 weeks to stroke-prone spontaneously hypertensive rats caused significantly decreased blood pressure as compared with a control group. Urinary 8-hydroxy-2'-deoxyguanosine was significantly lower in the lupeol group. Finally, lupeol
Marcin Broniatowski et al.
Journal of colloid and interface science, 381(1), 116-124 (2012-06-12)
Lupane type pentacyclic triterpenes (LTs) are pharmacologically active natural products isolated from different plants. They have broad spectrum of therapeutic action ranging from anticancer via anti-HIV, antibiotic to anti-inflammatory and anti-protozoal activity. Many scientific papers underline that the key stage
Development and validation of High Performance Liquid Chromatographic Method for the Simultaneous Determination of ?-sitosterol and Lupeol in Veronica cinerea Linn.
Shah, Willy, M. B. Kekare, and Vikas Vaidya.
International Journal of Pharma and Bio Sciences, 1 (3), 1-5 (2010)
Borhane Annabi et al.
Inflammopharmacology, 21(1), 91-99 (2012-06-19)
Local inflammation-induced extracellular matrix structural changes are a prerequisite to neoplastic invasion by pediatric intracranial tumors. Accordingly, increased expression of matrix metalloproteinases MMP-2 and MMP-9, two inflammation-induced matrix metalloproteinases (MMPs), may further aid the transformed cells either to infiltrate adjacent
Areej Mohammad Al-Taweel et al.
Molecules (Basel, Switzerland), 17(3), 2675-2682 (2012-03-07)
Nine compounds have been isolated for the first time from Celtis africana, namely trans-N-coumaroyltyramine (1), trans-N-feruloyltyramine (2), trans-N-caffeoyltyramine (3), lauric acid (4), oleic acid (5), palmitic acid (6), lupeol (7), β-sitosterol (8) and oleanolic acid (9), respectively. Their structures have
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