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关于此项目
经验公式(希尔记法):
C16H16N5NaO7S2
化学文摘社编号:
分子量:
477.45
EC Number:
264-915-9
UNSPSC Code:
51101500
MDL number:
Beilstein/REAXYS Number:
5711411
assay
≥98.0% (TLC)
impurities
≤5% water
solubility
H2O: 50 mg/mL, clear, light yellow
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
[Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O
InChI
1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1
InChI key
AZZMGZXNTDTSME-JUZDKLSSSA-M
General description
Chemical structure: β-lactam
Biochem/physiol Actions
Mode of Action: Inhibits bacterial cell wall synthesis.
Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
Other Notes
Broad spectrum third generation cephalosporin antibiotic.
This product has been replaced by C7912-SIGMA | Cefotaxime sodium salt potency: 916-964 μg per mg
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