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32677

鼠得克

Name: 鼠得克
Brand: SIAL

PESTANAL^®, analytical standard

别名:

3-(3-联苯基-1,2,3,4-四氢-1-萘基)-4-羟基-2H-1-苯并吡喃-2-酮, 3-(3-联苯基-1,2,3,4-四氢-1-萘基)-4-羟基香豆素

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关于此项目

经验公式（希尔记法）:

C₃₁H₂₄O₃

化学文摘社编号:

56073-07-5

分子量:

444.52

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329754289

EC Number:

259-978-4

Beilstein/REAXYS Number:

8360065

MDL number:

MFCD01632770

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属性

grade

analytical standard

Quality Level

100

product line

PESTANAL^®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

OC1=C(C2CC(Cc3ccccc23)c4ccc(cc4)-c5ccccc5)C(=O)Oc6ccccc16

InChI

1S/C31H24O3/c32-30-26-12-6-7-13-28(26)34-31(33)29(30)27-19-24(18-23-10-4-5-11-25(23)27)22-16-14-21(15-17-22)20-8-2-1-3-9-20/h1-17,24,27,32H,18-19H2

InChI key

FVQITOLOYMWVFU-UHFFFAOYSA-N

说明

General description

Difenacoum is a coumarin anticoagulant, which is developed as a rodenticide, in order to control warfarin‐resistant rodents.

Application

Difenacoum may be used as a reference standard in the determination of difenacoum in tissue samples using high performance liquid chromatography (HPLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

GHS06,GHS08,GHS09

signalword

Danger

hcodes

H300 + H310 + H330,H360D,H372,H410

pcodes

P202 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - STOT RE 1

target_organs

Blood

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

非剧毒-急性毒性1

危险化学品

农药列管产品

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Simple and rapid method for the determination of the diastereomers of difenacoum in blood and liver using high-performance liquid chromatography with fluorescence detection.

M J Kelly et al.

Journal of chromatography, 620(1), 105-112 (1993-10-22)

A rapid and sensitive high-performance liquid chromatographic method for the analysis of cis and trans diastereomers of the anticoagulant rodenticide difenacoum has been described. The methodology demonstrates potential for the analysis of diastereomers of related 4-hydroxycoumarin anticoagulants. Separations were achieved

Vitamin K antagonism of coumarin anticoagulation. A dehydrogenase pathway in rat liver is responsible for the antagonistic effect.

R Wallin

The Biochemical journal, 236(3), 685-693 (1986-06-15)

In the liver, it appears that there are two different pathways for vitamin K reduction. One pathway is irreversibly inhibited by coumarin anticoagulant drugs. The other pathway has been shown in the present study to be composed of enzymes that

Field trials of second-generation anticoagulants against difenacoum-resistant Norway rat population.

Greaves HJ, et al.

Epidem. Inf., 89(2), 295-301 (1982)

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全球贸易项目编号

货号	GTIN
32677-25MG	04061826716465

主要文件

鼠得克

PESTANAL^®, analytical standard