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Merck
CN

32677

鼠得克

PESTANAL®, analytical standard

别名:

3-(3-联苯基-1,2,3,4-四氢-1-萘基)-4-羟基-2H-1-苯并吡喃-2-酮, 3-(3-联苯基-1,2,3,4-四氢-1-萘基)-4-羟基香豆素

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关于此项目

经验公式（希尔记法）:
C31H24O3
化学文摘社编号:
56073-07-5
分子量:
444.52
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329754289
EC Number:
259-978-4
Beilstein/REAXYS Number:
8360065
MDL number:
MFCD01632770

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产品名称

鼠得克, PESTANAL®, analytical standard

InChI key

FVQITOLOYMWVFU-UHFFFAOYSA-N

InChI

1S/C31H24O3/c32-30-26-12-6-7-13-28(26)34-31(33)29(30)27-19-24(18-23-10-4-5-11-25(23)27)22-16-14-21(15-17-22)20-8-2-1-3-9-20/h1-17,24,27,32H,18-19H2

SMILES string

OC1=C(C2CC(Cc3ccccc23)c4ccc(cc4)-c5ccccc5)C(=O)Oc6ccccc16

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

Quality Level

100

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相关类别

Application

Difenacoum may be used as a reference standard in the determination of difenacoum in tissue samples using high performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Difenacoum is a coumarin anticoagulant, which is developed as a rodenticide, in order to control warfarin‐resistant rodents.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - STOT RE 1

target_organs

Blood

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

非剧毒-急性毒性1
危险化学品
农药列管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCL1265
BCCG1520
BCCD4919
BCBT5181

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Determination of coumarin anticoagulant rodenticide residues in animal tissue by high-performance liquid chromatography: I. Fluorescence detection using post-column techniques.
Hunter K, et al.
Journal of Chromatography A, 270, 267-276 (1983)
Helen Atterby et al.
Environmental toxicology and chemistry, 24(2), 318-323 (2005-02-22)
The present study investigated the whole-carcass residue carried by resistant and susceptible laboratory rat strains following 5, 10, or 20 d of feeding on a diet of 25 mg difenacoum/kg bait. The mean whole-carcass residue of difenacoum was determined by
Field trials of second-generation anticoagulants against difenacoum-resistant Norway rat population.
Greaves HJ, et al.
Epidem. Inf., 89(2), 295-301 (1982)
J E Gill et al.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 104(1), 29-36 (1993-01-01)
1. A new test for identifying levels of difenacoum resistance in the Norway rat is described, based upon the differential physiological response to difenacoum administration. 2. This test is based on changes in blood clotting activity over 4 days, following
Stefan Endepols et al.
Pest management science, 69(3), 409-413 (2012-04-25)
Field studies guided by genetic monitoring of Vkorc1 need to be done to implicate mutations conclusively with rodent control problems due to the presence of animals resistant to anticoagulant rodenticides. Rodent control success in relation to Vkorc1 genotypes in house
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