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经验公式(希尔记法):
C31H24O3
化学文摘社编号:
分子量:
444.52
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
259-978-4
Beilstein/REAXYS Number:
8360065
MDL number:
InChI key
FVQITOLOYMWVFU-UHFFFAOYSA-N
InChI
1S/C31H24O3/c32-30-26-12-6-7-13-28(26)34-31(33)29(30)27-19-24(18-23-10-4-5-11-25(23)27)22-16-14-21(15-17-22)20-8-2-1-3-9-20/h1-17,24,27,32H,18-19H2
SMILES string
OC1=C(C2CC(Cc3ccccc23)c4ccc(cc4)-c5ccccc5)C(=O)Oc6ccccc16
grade
analytical standard
product line
PESTANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
agriculture
environmental
format
neat
Quality Level
General description
Difenacoum is a coumarin anticoagulant, which is developed as a rodenticide, in order to control warfarin‐resistant rodents.
Application
Difenacoum may be used as a reference standard in the determination of difenacoum in tissue samples using high performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - STOT RE 1
target_organs
Blood
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
非剧毒-急性毒性1
危险化学品
农药列管产品
此项目有
M J Kelly et al.
Journal of chromatography, 620(1), 105-112 (1993-10-22)
A rapid and sensitive high-performance liquid chromatographic method for the analysis of cis and trans diastereomers of the anticoagulant rodenticide difenacoum has been described. The methodology demonstrates potential for the analysis of diastereomers of related 4-hydroxycoumarin anticoagulants. Separations were achieved
Field trials of second-generation anticoagulants against difenacoum-resistant Norway rat population.
Greaves HJ, et al.
Epidem. Inf., 89(2), 295-301 (1982)
R Wallin
The Biochemical journal, 236(3), 685-693 (1986-06-15)
In the liver, it appears that there are two different pathways for vitamin K reduction. One pathway is irreversibly inhibited by coumarin anticoagulant drugs. The other pathway has been shown in the present study to be composed of enzymes that
S C Smolinske et al.
Pediatrics, 84(3), 490-494 (1989-09-01)
This prospective study was undertaken to determine the incidence, severity, time of onset, and duration of coagulopathy in children following accidental ingestion of long-acting anticoagulant rodenticides, often called "superwarfarins." Of 110 children, who ingested superwarfarins and in whom one or
S Terneu et al.
Acta clinica Belgica, 58(4), 241-244 (2003-11-26)
A 36-year-old woman presented to the Emergency Room because of abdominal pain associated with hematuria and red blood blending to stool. On admission, the physical examination revealed abdominal tenderness and diffuse cutaneous hematoma. The laboratory findings showed abnormal clotting tests
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