Merck
CN

32991

Supelco

拉诺康唑

VETRANAL®, analytical standard

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别名:
2-[4-(2-氯苯基)-1,3-二硫戊环-2-亚基]-2-咪唑-1-基-乙腈
经验公式(希尔记法):
C14H10ClN3S2
分子量:
319.83
MDL编号:
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

产品线

VETRANAL®

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

clinical testing

格式

neat

储存温度

2-8°C

SMILES字符串

Clc1ccccc1C2CS\C(S2)=C(\C#N)n3ccnc3

InChI

1S/C14H10ClN3S2/c15-11-4-2-1-3-10(11)13-8-19-14(20-13)12(7-16)18-6-5-17-9-18/h1-6,9,13H,8H2/b14-12+

InChI key

ZRTQSJFIDWNVJW-WYMLVPIESA-N

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一般描述

Lanoconazole is a member of the imidazole family and an antifungal agent, which finds applications as an antidermatophytic drug.

应用

Lanoconazole may be used as a reference standard in the determination of lanoconazole in pharmaceutical formulations using high-performance liquid chromatography coupled with an ultraviolet detector (HPLC-UV).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

法律信息

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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Toshihiro Akihisa et al.
Journal of oleo science, 59(7), 351-360 (2010-06-02)
The content and composition of triterpene alcohol fractions of the non-saponifiable lipids (NSL) along with the fatty acid composition of the kernel fats (n-hexane extracts) of the shea tree (Vitellaria paradoxa; Sapotaceae) were determined for 36 samples from seven sub-Saharan
Allergic contact dermatitis due to lanoconazole with no cross-reactivity to other imidazoles.
S Taniguchi et al.
Dermatology (Basel, Switzerland), 196(3), 366-366 (1998-06-11)
Daisuke Todokoro et al.
Cornea, 38(2), 238-242 (2018-11-14)
Fungal keratitis can be difficult to medically treat. Topical antifungals are usually applied empirically as the initial option in treating fungal keratitis. Natamycin (NAT) and/or voriconazole (VRCZ) have been widely used in the treatment of fungal keratitis. However, Fusarium solani
Yoshiyuki Tatsumi et al.
Microbiology and immunology, 46(7), 433-439 (2002-09-12)
We developed a new technique for culture study that successfully recovers fungi from drug-treated skin tissues, in which tissue specimens were homogenized, dialyzed against water, digested with trypsin, and then washed with PBS, to eliminate the drug that remaining in
A Phani Kumar et al.
Journal of pharmaceutical and biomedical analysis, 50(3), 535-537 (2009-06-03)
An isocratic normal phase high-performance liquid chromatographic (NP-HPLC) method has been developed and validated for the quantitation of Z-isomer in lanoconazole. Separation was achieved with a Thermo Hypersil Silica column. The ratio of 2-propanol, n-hexane and triethylamine in the mobile

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