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Merck
CN

34007

羟基甲硝唑

VETRANAL®, analytical standard

别名:

1-(2-羟乙基)-2-羟甲基-5-硝基咪唑, MNZOH, 羟基甲硝唑

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关于此项目

经验公式(希尔记法):
C6H9N3O4
化学文摘社编号:
分子量:
187.15
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

OCCn1c(CO)ncc1[N+]([O-])=O

InChI

1S/C6H9N3O4/c10-2-1-8-5(4-11)7-3-6(8)9(12)13/h3,10-11H,1-2,4H2

InChI key

AEHPOYAOLCAMIU-UHFFFAOYSA-N

General description

羟基甲硝唑是一种基因毒性、致癌和致突变的硝基咪唑类药物,可作为广谱兽药治疗和预防农场动物的细菌和原虫感染疾病。

Application

羟基甲硝唑可作为标准品,通过超高效液相色谱 (UPLC) -四极杆/线性离子阱质谱法 (UPLC-Qtrap-MS/MS)和超高效液相色谱 -飞行时间质谱 (TOF) 法测定水样和肉类基质中的羟基甲硝唑抗生素。
有关合适仪器技术的更多信息,请参考产品′s分析证书。如需进一步支持,请联系技术服务。

Other Notes

在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析(使用数字化外标)。可查看该物质的NMR谱图,只需点击几次鼠标,就能进行在线样品比对。欢迎点击了解更多,开启免费试用之旅。

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany


存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

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P Hall et al.
Archives of disease in childhood, 58(7), 529-531 (1983-07-01)
Twenty four neonates at high risk of anaerobic sepsis were treated with intravenous metronidazole, 7.5 mg/kg, 8 hourly, for a mean period of 5 days. The highest observed concentration after the first dose (mean +/- SD) 9.6 +/- 4.0 mg/l
M J Pavicić et al.
Antimicrobial agents and chemotherapy, 35(5), 961-966 (1991-05-01)
Interactions between metronidazole and amoxicillin, metronidazole and its hydroxymetabolite, and amoxicillin and the hydroxymetabolite of metronidazole were investigated with checkerboard titrations in combination with accurately determined MICs and MBCs. Actinobacillus actinomycetemcomitans was used as the test organism. Synergism was found
S Loft et al.
Human & experimental toxicology, 9(3), 155-159 (1990-05-01)
1 The disposition of metronidazole and its major metabolites was compared in 11 subjects aged 86 +/- 6 years and 8 aged 30 +/- 6 years. 2 The plasma clearance of metronidazole was 1.20 +/- 0.53 and 1.25 +/- 0.22



全球贸易项目编号

货号GTIN
34007-10MG-R04061826752845