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安全信息

34392

Supelco

甲基二溴戊二腈

analytical standard

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别名:
1,2-二溴-2,4-二氰丁烷, 1-溴-1-(溴甲基)-1,3-丙烷二甲腈, 2-溴-2-(溴甲基)戊二腈
经验公式（希尔记法）:
C6H6Br2N2
CAS号:
35691-65-7
分子量:
265.93
EC 号:
252-681-0
MDL编号:
MFCD00072483
PubChem化学物质编号:
329754978
NACRES:
NA.24

等级

analytical standard

质量水平

100

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

51-55 °C

应用

environmental

格式

neat

储存温度

2-8°C

SMILES字符串

BrCC(Br)(CCC#N)C#N

InChI

1S/C6H6Br2N2/c7-4-6(8,5-10)2-1-3-9/h1-2,4H2

InChI key

DHVLDKHFGIVEIP-UHFFFAOYSA-N

相关类别

一般描述

Methyldibromoglutaronitrile (MDBGN) is a bromine-containing preservative and a clinically significant allergen as investigated from animal/human clinical studies.
Methyldibromoglutaronitrile can be generally used as a preservative in the cosmetic industry for many skin care products.

应用

Methyldibromoglutaronitrile may be used as an analytical reference standard for the quantification of the analyte in cosmetic products using ultra performance liquid chromatography (UPLC) coupled to inductively coupled plasma mass spectrometry (ICP-MS) and gas chromatography followed by mass spectrometry technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

象形图

CorrosionExclamation mark
GHS05,GHS07

警示用语：

Danger

危险声明

H302 - H314

危险分类

Acute Tox. 4 Oral - Skin Corr. 1B

储存分类代码

8A - Combustible, corrosive hazardous materials

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

农药列管产品

分析证书(COA)

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示例

T1503
货号
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25G
包装规格/数量

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1000309185

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Louise Arup Fischer et al.
Contact dermatitis, 61(4), 201-208 (2009-10-15)
Allergic contact dermatitis is common and can be prevented. The relationship between thresholds for patch tests and the repeated open application test (ROAT) is unclear. It would be desirable if patch test and ROAT data from already sensitized individuals could
Annice Heratizadeh et al.
Contact dermatitis, 62(6), 330-337 (2010-06-19)
While the use of methyldibromo glutaronitrile (MDBGN) in leave-on products is clearly associated with high sensitization or elicitation risk, such a clear-cut relation could be questioned with regard to rinse-off products. The objective of this study was to find a
Axel Schnuch et al.
Contact dermatitis, 56(6), 331-337 (2007-06-20)
Although genetic factors probably account for differences in susceptibility to contact allergy, they have not yet been identified, partly due to an insufficient understanding of 'susceptibility'. Regarding polysensitization (PS) as a sign of increased susceptibility, we studied the relationship between
A C De Groot et al.
Journal of the American Academy of Dermatology, 35(5 Pt 1), 743-747 (1996-11-01)
Euxyl K 400 is a preservative system for cosmetics and toiletries that contains phenoxyethanol and methyldibromoglutaronitrile in a 4:1 ratio. In The Netherlands, Italy, and Germany, the prevalence of allergy to Euxyl K 400 has risen in the past 4
Jakob Torp Madsen et al.
Contact dermatitis, 63(4), 209-214 (2010-08-25)
Ethosomes and liposomes are ultra-small vesicles capable of encapsulating drugs and cosmetic ingredients for topical use, thereby potentially increasing bioavailability and clinical efficacy. So far, few reports have suggested that formulation of cosmetic ingredients in vesicular carrier systems may increase
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