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Merck
CN

35405

Supelco

α-Zearalanol solution

~10 μg/mL in acetonitrile, analytical standard

别名:

(3S,7R)-3,4,5,6,7,8,9,10,11,12-Decahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one solution, 2,4-Dihydroxy-6-(6α,10-dihydroxyundecyl)benzoic acid μ-lactone solution

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关于此项目

经验公式（希尔记法）:
C18H26O5
化学文摘社编号:
26538-44-3
分子量:
322.40
EC 号:
200-835-2
MDL编号:
MFCD00864182
UNSPSC代码:
85151701
PubChem化学物质编号:
329755162

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等级

analytical standard

保质期

limited shelf life, expiry date on the label

药品控制

regulated under CDSA - not available from Sigma-Aldrich Canada

存货情况

not available in Canada

浓度

~10 μg/mL in acetonitrile

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

cleaning products
cosmetics
food and beverages
personal care

包装形式

single component solution

储存温度

−20°C

SMILES字符串

C[C@H]1CCC[C@H](O)CCCCCc2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14+/m0/s1

InChI key

DWTTZBARDOXEAM-GXTWGEPZSA-N

一般描述

α-Zearalanol is a resorcyclic acid lactone. It is a plant derived, nonsteroidal phytoestrogen, often used as a dietary supplement.

应用

α-Zearalanol may be used as an analytical reference standard for the determination of the analyte in traditional Chinese medicines, human and animal urine by various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

分析说明

purity : ≥97.0% (HPLC)

象形图

FlameExclamation mark
GHS02,GHS07

警示用语：

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

35.6 °F - closed cup

闪点(°C)

2.0 °C - closed cup

法规信息

危险化学品
高风险级别生物产品--毒素类产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCK8403
BCCH2931
BCCF0197
BCCB8524
BCCB1173

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A rapid method for simultaneous determination of zearalenone, α-zearalenol, β-zearalenol, zearalanone, α-zearalanol and β-zearalanol in traditional Chinese medicines by ultra-high-performance liquid chromatography-tandem mass spectrometry.
Han Z, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 879(5-6), 411-420 (2011)
Nidia V Valenzuela-Grijalva et al.
Journal of the science of food and agriculture, 92(7), 1362-1367 (2011-12-07)
The effect of zeranol implantation strategy on intramuscular fat, fatty acid profile and cholesterol content of the longissimus dorsi muscle of hair lambs was studied. Four treatments were tested: C, control group; Z12, 12 mg zeranol; Z24, 24 mg zeranol
Lu Liu et al.
Acta biochimica et biophysica Sinica, 44(8), 669-677 (2012-06-26)
Pre-osteoblast MC3T3-E1 cells were cultured in hyaluronic acid-modified chitosan/collagen/nano-hydroxyapatite (HA-CS/Col/nHAP) composite scaffolds and treated with phytoestrogen α-zearalanol (α-ZAL) to improve bone tissue formation for bone tissue engineering. Perfusion and dynamic strain were applied to three-dimensional (3D) cultured cells, which simulates
Caroline Prouillac et al.
Toxicology and applied pharmacology, 259(3), 366-375 (2012-02-09)
Zearalenone (ZEN) is a non-steroid estrogen mycotoxin produced by numerous strains of Fusarium which commonly contaminate cereals. After oral administration, ZEN is reduced via intestinal and hepatic metabolism to α- and β-zearalenol (αZEL and βZEL). These reduced metabolites possess estrogenic
Elisa V Bandera et al.
The Science of the total environment, 409(24), 5221-5227 (2011-10-07)
Despite extensive research and interest in endocrine disruptors, there are essentially no epidemiologic studies of estrogenic mycotoxins, such as zeranol and zearalenone (ZEA). ZEA mycoestrogens are present in grains and other plant foods through fungal contamination, and in animal products
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