38332
东莨菪内酯
analytical standard
别名:
6-甲氧基伞形酮, 7-羟基-6-甲氧基-2H-1-苯并吡喃-2-酮, 7-羟基-6-甲氧基香豆素, 七叶亭-6-甲醚, 东莨菪亭, 东莨菪内酯, 柯阿托酸, 莨菪亭, 钩吻酸
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关于此项目
经验公式（希尔记法）:
C10H8O4
化学文摘社编号:
分子量:
192.17
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
202-171-9
Beilstein/REAXYS Number:
156296
MDL number:
产品名称
东莨菪内酯, analytical standard
InChI
1S/C10H8O4/c1-13-9-4-6-2-3-10(12)14-8(6)5-7(9)11/h2-5,11H,1H3
SMILES string
COc1cc2C=CC(=O)Oc2cc1O
InChI key
RODXRVNMMDRFIK-UHFFFAOYSA-N
grade
analytical standard
assay
≥97.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
203-205 °C (lit.)
application(s)
food and beverages
format
neat
storage temp.
2-8°C
Quality Level
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Biochem/physiol Actions
东莨菪素通过促进 LPL 基因的转录，显著增强脂肪细胞中脂蛋白脂肪酶的活性。它还部分逆转 TNF-α 对 LPL 的抑制作用。
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Scopoletin may be used as a reference standard for the determination of scopoletin in:
- Roots, stems, branches, and seeds as well as leaves of Chimonanthus nitens Oliv. by ultra-high performance liquid chromatography/tandem quadrupole-time-of-flight mass spectrometry (UHPLC-QTOF-MS/MS) equipped with modified mass deflect filter or diagnostic product ions/neutral loss filter.
- Canscora decussate (South Indian Shankhpushpi) extracts by high performance thin layer chromatography (HPTLC).
- Morinda tinctoria Roxb. leaf by HPTLC in conjunction with HPLC and gas chromatography with MS.
General description
Scopoletin is a coumarin compound and pharmacologically active chemical that is found in various plant species.
Other Notes
This compound is commonly found in plants of the genus: achillea angelica glycyrrhiza lycium pimpinella
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Rapid validated high performance thin layer chromatography method for simultaneous estimation of mangiferin and scopoletin in Canscora decussata (South Indian Shankhpushpi) extract.
Sethiya NK, et al.
Revista Brasileira de Farmacognosia, 25(3), 193-198 (2015)
Use of scopoletin to inhibit the production of inflammatory cytokines through inhibition of the I?B/NF-?B signal cascade in the human mast cell line HMC-1.
Moon PD, et al.
European Journal of Pharmacology, 555(2-3), 218-225 (2007)
Comprehensive profiling and characterization of coumarins from roots, stems, leaves, branches, and seeds of Chimonanthus nitens Oliv. using ultra-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry combined with modified mass defect filter.
Tan T, et al.
Journal of Pharmaceutical and Biomedical Analysis, 141(2-3), 140-148 (2017)
Structural characterization and discrimination of Chimonanthus nitens Oliv. leaf from different geographical origins based on multiple chromatographic analysis combined with chemometric methods.
Huang WP, et al.
Journal of Pharmaceutical and Biomedical Analysis, 154(2-3), 236-244 (2018)
M Baz et al.
Journal of applied microbiology, 112(4), 782-792 (2012-02-02)
The early molecular events underlying the elicitation of plant defence reactions by Gram-positive bacteria are relatively unknown. In plants, calcium and reactive oxygen species are commonly involved as cellular messengers of a wide range of biotic stimuli from pathogenic to
实验方案
HPTLC fingerprinting enables rapid identification of passion flower with related reference materials.
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