42612
和厚朴酚
analytical standard
别名:
5,3′-Diallyl-2,4′-dihydroxybiphenyl, NSC 293100
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关于此项目
经验公式（希尔记法）:
C18H18O2
化学文摘社编号:
分子量:
266.33
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:
产品名称
和厚朴酚, analytical standard
InChI
1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2
SMILES string
Oc1ccc(cc1CC=C)-c2cc(CC=C)ccc2O
InChI key
FVYXIJYOAGAUQK-UHFFFAOYSA-N
grade
analytical standard
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
storage temp.
2-8°C
Quality Level
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Biochem/physiol Actions
和厚朴酚是来自木兰提取物的天然联苯新木脂素。它具有抗血管生成、抗肿瘤和抗焦虑的作用。
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 2 - Eye Dam. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Ankit Kumar et al.
Future medicinal chemistry, 5(7), 809-829 (2013-05-09)
Honokiol (3,5-di-(2-propenyl)-1,1-biphenyl-2,2-diol) is a natural bioactive neolignan isolated from the genus Magnolia. In recent studies, honokiol has been observed to have anti-angiogenic, anticancer, anti-inflammatory, neuroprotective and GABA-modulating properties in vitro and in preclinical models. Honokiol and its analogs target multiple
Wei Tian et al.
Die Pharmazie, 67(10), 811-816 (2012-11-10)
Honokiol is a small-molecule pharmacologically active component which has various medicinal applications. Increasing interest is paid on its multifunctional anti-tumor effects including inducing tumor cell death, anti-angiogenesis, anti-migration and anti-multiple drug resistance. We addressed a brief summary of the anti-tumor
Haiquan Wang et al.
Neuropharmacology, 86, 9-21 (2014-06-29)
Recently, increasing evidence has shown that cell cycle activation is a key factor of neuronal death and neurological dysfunction after traumatic brain injury (TBI). This study aims to investigate the effects of Honokiol, a cell cycle inhibitor, on attenuating the
Wei-Zhe Liang et al.
Chemico-biological interactions, 221, 13-23 (2014-08-12)
Honokiol, an active constituent of oriental medicinal herb Magnolia officinalis, caused Ca(2+) mobilization and apoptosis in different cancer cells. In vivo, honokiol crossed the blood-brain or -cerebrospinal fluid barrier, suggesting that it may be an effective drug for the treatment
S Arora et al.
Current molecular medicine, 12(10), 1244-1252 (2012-07-28)
Honokiol (3',5-di-(2-propenyl)-1,1'-biphenyl-2,4'-diol) is a bioactive natural product derived from Magnolia spp. Recent studies have demonstrated anti-inflammatory, anti-angiogenic, anti-oxidative and anticancer properties of honokiol in vitro and in preclinical models. Honokiol targets multiple signaling pathways including nuclear factor kappa B (NF-κB)
商品
Quantitative HPLC-UV analysis of honokiol, magnolol, and glycyrrhizic acid in Huoxiang Zhengqi Shui following the Chinese Pharmacopoeia draft.
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