42899
(+)-异紫堇定碱 盐酸盐
analytical standard
别名:
11-Hydroxy-1,2,10-trimethoxyaporphine, Isocorydine hydrochloride, Luteanine
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关于此项目
经验公式（希尔记法）:
C20H23NO4 · HCl
化学文摘社编号:
分子量:
377.86
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:
InChI key
ZWSKLEMBDRWSNZ-ZOWNYOTGSA-N
SMILES string
OC1=C2C(C[C@@]3([H])C4=C2C(OC)=C(OC)C=C4CCN3C)=CC=C1OC.Cl
InChI
1S/C20H23NO4.ClH/c1-21-8-7-12-10-15(24-3)20(25-4)18-16(12)13(21)9-11-5-6-14(23-2)19(22)17(11)18;/h5-6,10,13,22H,7-9H2,1-4H3;1H/t13-;/m0./s1
grade
analytical standard
assay
≥98.0% (HPLC)
optical activity
[α]/D 180±10°, c = 0.1 in methanol
shelf life
limited shelf life, expiry date on the label
impurities
≤5.0% water
mp
215-218 °C (dec.) (lit.)
application(s)
food and beverages
format
neat
Quality Level
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General description
(+)-Isocorydine is classified under the family of aporphine alkaloids, which are ubiquitously found in various plants. This natural tetrahydroisoquinoline alkaloid is most commonly present in species belonging to the Papaveraceae, Menispermaceae, and Annonaceae families.
Application
(+)-Isocorydine hydrochloride may be used as a precursor for the preparation of (+)-isocorydine, which in turn can be used as an analytical standard for the determination of the analyte in biological samples, and roots and aerial parts of Cryptocarya alba tree species by liquid chromatography based techniques.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
Design, synthesis, and anticancer properties of isocorydine derivatives
Yan Q, et al.
Bioorganic & Medicinal Chemistry, 25(24), 6542-6553 (2017)
Phytochemical analysis of alkaloids from the Chilean endemic tree Cryptocarya alba
Castro-Saavedra S, et al.
Journal of the Chilean Chemical Society, 61(3), 3076-3080 (2016)
Changchuan Guo et al.
Xenobiotica; the fate of foreign compounds in biological systems, 42(5), 466-476 (2012-02-23)
A rapid and sensitive method for the determination of isocorydine in rat plasma and tissues was developed using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The biological samples were processed by extracting with diethyl ether-dichloromethane (3:2, v/v) and tetrahydropulmatine was used as
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