42899
(+)-异紫堇定碱 盐酸盐
analytical standard
别名:
11-Hydroxy-1,2,10-trimethoxyaporphine, Isocorydine hydrochloride, Luteanine
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关于此项目
经验公式(希尔记法):
C20H23NO4 · HCl
化学文摘社编号:
分子量:
377.86
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
方案
≥98.0% (HPLC)
旋光性
[α]/D 180±10°, c = 0.1 in methanol
保质期
limited shelf life, expiry date on the label
杂质
≤5.0% water
mp
215-218 °C (dec.) (lit.)
应用
food and beverages
包装形式
neat
SMILES字符串
OC1=C2C(C[C@@]3([H])C4=C2C(OC)=C(OC)C=C4CCN3C)=CC=C1OC.Cl
InChI
1S/C20H23NO4.ClH/c1-21-8-7-12-10-15(24-3)20(25-4)18-16(12)13(21)9-11-5-6-14(23-2)19(22)17(11)18;/h5-6,10,13,22H,7-9H2,1-4H3;1H/t13-;/m0./s1
InChI key
ZWSKLEMBDRWSNZ-ZOWNYOTGSA-N
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一般描述
(+)-Isocorydine is classified under the family of aporphine alkaloids, which are ubiquitously found in various plants. This natural tetrahydroisoquinoline alkaloid is most commonly present in species belonging to the Papaveraceae, Menispermaceae, and Annonaceae families.
应用
(+)-Isocorydine hydrochloride may be used as a precursor for the preparation of (+)-isocorydine, which in turn can be used as an analytical standard for the determination of the analyte in biological samples, and roots and aerial parts of Cryptocarya alba tree species by liquid chromatography based techniques.
警示用语:
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
涉药品监管产品
此项目有
Phytochemical analysis of alkaloids from the Chilean endemic tree Cryptocarya alba
Castro-Saavedra S, et al.
Journal of the Chilean Chemical Society, 61(3), 3076-3080 (2016)
Design, synthesis, and anticancer properties of isocorydine derivatives
Yan Q, et al.
Bioorganic & Medicinal Chemistry, 25(24), 6542-6553 (2017)
Changchuan Guo et al.
Xenobiotica; the fate of foreign compounds in biological systems, 42(5), 466-476 (2012-02-23)
A rapid and sensitive method for the determination of isocorydine in rat plasma and tissues was developed using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The biological samples were processed by extracting with diethyl ether-dichloromethane (3:2, v/v) and tetrahydropulmatine was used as
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