44864
顺式-5,8,11,14,17-二十碳五烯酸
analytical standard
别名:
EPA, 二十碳五烯酸
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关于此项目
线性分子式:
CH3(CH2CH=CH)5(CH2)3CO2H
化学文摘社编号:
分子量:
302.45
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1714433
biological source
fish oil
Quality Level
grade
analytical standard
assay
≥98.5% (GC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
refractive index
n20/D 1.4977 (lit.)
mp
−54-−53 °C (lit.)
density
0.943 g/mL at 25 °C (lit.)
format
neat
functional group
carboxylic acid
storage temp.
−20°C
SMILES string
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O
InChI
1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-,16-15-
InChI key
JAZBEHYOTPTENJ-JLNKQSITSA-N
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General description
顺式-5,8,11,14,17-二十碳五烯酸属于长链 omega-3多不饱和脂肪酸类。它在人体中通过必须脂肪酸 alpha-亚麻酸合成。
Application
本分析标准品还可适用于以下情况：
- 优化毛细管区带电泳联用直接吸收紫外检测法(CZE-UV)测定10个不同的商业omega-3补充剂样本中在甲基化后的二十碳五烯酸和二十二碳六烯酸
- 通过高效液相色谱-电化学检测（HPLC-ECD）同时测定人血浆样品中的二十碳五烯酸，二十二碳六烯酸和花生四烯酸
- 通过高效液相色谱联用串联质谱（HPLC-MS/MS）分离，鉴定和量化人血浆样品中的二十碳五烯酸，二十二碳六烯酸和花生四烯酸
Biochem/physiol Actions
5-脂氧合酶抑制剂；减少凝血噁烷 A2 生成。
Packaging
无底玻璃瓶。内含物装在插入的融合锥内。
Other Notes
有关合适的仪器技术的更多信息，请参阅产品′的检验报告。想要获得更多支持，请联系技术服务部。
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
200.1 °F - closed cup
flash_point_c
93.4 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hyeon Ho Kim et al.
Journal of lipid research, 47(5), 921-930 (2006-02-10)
Skin aging can be attributed to photoaging (extrinsic) and chronological (intrinsic) aging. Photoaging and intrinsic aging are induced by damage to human skin attributable to repeated exposure to ultraviolet (UV) irradiation and to the passage of time, respectively. In our
Wendy L Hall et al.
The Journal of nutrition, 138(2), 287-291 (2008-01-22)
Diets rich in eicosapentaenoic acid [EPA; 20:5(n-3)] are associated with decreased arterial stiffness, but postprandial effects on vascular function are unknown. We investigated whether an EPA-enriched high-fat meal could improve postprandial vascular function. Seventeen healthy men ingested 2 test meals
Hyeon Ho Kim et al.
Journal of lipid research, 46(8), 1712-1720 (2005-06-03)
Ultraviolet (UV) irradiation regulates UV-responsive genes, including matrix metalloproteinases (MMPs). Moreover, UV-induced MMPs cause connective tissue damage and the skin to become wrinkled and aged. Here, we investigated the effect of eicosapentaenoic acid (EPA), a dietary omega-3 fatty acid, on
Botond Borcsa et al.
Fitoterapia, 82(3), 365-368 (2010-11-16)
Processed aconite drugs are widely used in Eastern medicine as painkillers and antirheumatic agents. It is known that the traditional processing of aconite drugs increases the amount of lipo-alkaloids. In order to obtain information about the pharmacological potential of these
S Sipka et al.
Clinical immunology and immunopathology, 79(3), 224-228 (1996-06-01)
Free eicosapentaenoic acid (EPA) was found to inhibit dose dependently the chemiluminescence of human neutrophil granulocytes phagocytosing zymosan and their chemotaxis induced by C5a-containing zymosan-activated serum (ZAS) and platelet-activating factor. Rigidification of plasma membranes in the ZAS-treated cells could be
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 44864-500MG | 04061832312682 |
| 44864-100MG | 04061832312675 |
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