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Merck
CN

67770

甲基α-D-吡喃甘露糖苷

suitable for microbiology, ≥99.0%, enables differentiation between species of Listeria

别名:

α-甲基D-甘露糖苷

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关于此项目

经验公式(希尔记法):
C7H14O6
化学文摘社编号:
分子量:
194.18
UNSPSC Code:
41106212
NACRES:
NA.85
PubChem Substance ID:
EC Number:
210-502-3
Beilstein/REAXYS Number:
81566
MDL number:
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Quality Level

assay

≥99.0% (sum of enantiomers, HPLC), ≥99.0%

form

powder

optical activity

[α]20/D 77.0 to 82.0°, c = 10% in H2O

mol wt

194.18 g/mol

mp

187-195 °C, 193-196 °C (lit.)

solubility

H2O: 0.1 g/mL, clear, colorless

application(s)

microbiology

SMILES string

CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O

InChI

1S/C7H14O6/c1-12-7-6(11)5(10)4(9)3(2-8)13-7/h3-11H,2H2,1H3/t3-,4-,5+,6+,7+/m1/s1

InChI key

HOVAGTYPODGVJG-VEIUFWFVSA-N

General description

Methyl α-D-mannopyranoside is a compound that belongs to the class of organic compounds known as o-glycosyl compounds. It is used for the differentiation of Listeria species, Listeria monocytogenes, Listeria innocua, and Listeria welshimeri can ferment the sugar, producing acid which can be identified using an appropriate pH indicator. It has been used to synthesize a series of tri- and tetrahydroxylated seven-membered imino sugars in a study that worked towards a stable Noeuromycin (glycosyl cation mimic that strongly inhibits glycosidases) analog with a D-manno configuration. It has also been used in a study to investigate the primary mannose-binding site of Pradimicin A. (antifungal agent)

Application

Methyl α-D-mannopyranoside can be used to identify different species of Listeria based on their ability to ferment the sugar.

Other Notes

抑制亲和素和内源性凝集素的结合


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

404.1 °F

flash_point_c

206.74 °C

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Culture media provides a habitat with suitable nutrients, energy sources, and certain environmental conditions for the growth of microorganisms. The components of the culture media range from simple sugars to peptones, salts, antibiotics, and complex indicators.


Oliver Schwardt et al.
Bioorganic & medicinal chemistry, 19(21), 6454-6473 (2011-10-04)
Urinary tract infection (UTI) caused by uropathogenic Escherichia coli (UPEC) is one of the most prevalent infectious diseases. Particularly affected are women, who have a 40-50% risk to experience at least one symptomatic UTI episode at some time during their
Prevention of nonspecific binding of avidin.
R C Duhamel et al.
Methods in enzymology, 184, 201-207 (1990-01-01)
Karen T Welch et al.
Bioorganic & medicinal chemistry letters, 18(24), 6573-6575 (2008-11-08)
A virtual screening approach was used to identify new glycomimetics. The National Cancer Institute Diversity Set was docked into the carbohydrate binding site of the lectin concanavalin A (ConA). The resulting poses were analyzed and 19 molecules were tested for



全球贸易项目编号

货号GTIN
67770-25G04061832748450
67770-500G04061833440865
67770-100G04061832748443