69545
Kaempferide
analytical standard
别名:
3,5,7-Trihydroxy-4′-methoxyflavone, KF, 4′-Methoxy-3,5,7-trihydroxyflavone
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关于此项目
经验公式（希尔记法）:
C16H12O6
化学文摘社编号:
分子量:
300.26
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-738-4
Beilstein/REAXYS Number:
305378
MDL number:
InChI key
SQFSKOYWJBQGKQ-UHFFFAOYSA-N
InChI
1S/C16H12O6/c1-21-10-4-2-8(3-5-10)16-15(20)14(19)13-11(18)6-9(17)7-12(13)22-16/h2-7,17-18,20H,1H3
SMILES string
COc1ccc(cc1)C2=C(O)C(=O)c3c(O)cc(O)cc3O2
grade
analytical standard
assay
≥99.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
storage temp.
2-8°C
Quality Level
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General description
Kaempferide is a naturally occurring, O-methylated flavonol found in Kaempferia galanga. It exhibits a variety of pharmacological effects such as anti-inflammatory, anti-viral, anti-oxidant, anti-bacterial and antitumor properties.
Application
Kaempferide may be used as an analytical reference standard for the quantification of the analyte in propolis and traditional Chinese medicine Zuo Gui Wan using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
This compound is commonly found in plants of the genus: arnica silybum
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
A combined HPLC-PDA and HPLC-MS method for quantitative and qualitative analysis of 10 major constituents in the traditional Chinese medicine Zuo Gui Wan
Liang X, et al.
Journal of Pharmaceutical and Biomedical Analysis, 49(4), 931-936 (2009)
Kaempferide prevents titanium particle induced osteolysis by suppressing JNK activation during osteoclast formation
Jiao Z, et al.
Scientific Reports, 7(1) (2017)
Ehab Ghazy et al.
European journal of medicinal chemistry, 200, 112338-112338 (2020-06-05)
Histone modifying proteins, specifically histone deacetylases (HDACs) and bromodomains, have emerged as novel promising targets for anticancer therapy. In the current work, based on available crystal structures and docking studies, we designed dual inhibitors of both HDAC6/8 and the bromodomain
Selective analysis of phenolic compounds in propolis by HPLC?MS/MS
Medana C, et al.
Phytochemical Analysis, 19(1), 32-39 (2008)
Cuiping Zhang et al.
Journal of food science, 82(7), 1602-1607 (2017-06-01)
Brazilian green propolis is known as an appreciable natural antioxidant with abundant polyphenolic compounds. For quality control, a fingerprint-efficacy study of Brazilian green propolis was carried out in this work. Chemical fingerprints of Brazilian green propolis from 22 different sources
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