81242
聚（乙二醇）
tested according to Ph. Eur., 4,000
别名:
Macrogol 4,000, PEG
Agency
tested according to Ph. Eur.
质量水平
表单
solid
分子量
3500-4500
应用
pharmaceutical (small molecule)
SMILES字符串
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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一般描述
聚（乙二醇）（PEG）是一种无毒的水溶性聚合物。PEG 术语用于分子量低于 20000 的聚合物链，而聚（环氧乙烷）（PEO）是指较高分子量的聚合物。PEG 具有多种生物医学应用。它与 α-环糊精形成复合物。已有研究报道了通过介孔二氧化硅（MS）模板法工程化 PEG 水凝胶颗粒。
应用
聚（乙二醇）可用于以下研究：
- 用于修饰蛋白质形成循环寿命增加、免疫原性和抗原性降低的缀合物。
- 用于蛋白质扩散控制运输的水凝胶的制备。
- 聚（乙二醇）二甲基丙烯酸酯（PEGDM）的制备。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Stephanie J Bryant et al.
Annals of biomedical engineering, 32(3), 407-417 (2004-04-21)
In approaches to tissue engineer articular cartilage, an important consideration for in situ forming cell carriers is the impact of mechanical loading on the cell composite structure and function. Photopolymerized hydrogel scaffolds based on poly(ethylene glycol) (PEG) may be synthesized
Complex formation between poly (ethylene glycol) and α-cyclodextrin.
Harada A and Kamachi M.
Macromolecules, 23(10), 2821-2823 (1990)
The clinical efficacy of poly (ethylene glycol)-modified proteins.
Fuertges F and Abuchowski A.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 11(1), 139-148 (1990)
N A Peppas et al.
Journal of controlled release : official journal of the Controlled Release Society, 62(1-2), 81-87 (1999-10-16)
The use of hydrogels as carriers for protein delivery has been a subject of significant recent research. In our recent work, we have shown that diffusion controlled delivery of proteins from hydrogels containing poly(ethylene glycol) (PEG) can be possible and
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
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