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Merck
CN

81619

四氢嘧啶

≥95.0% (HPLC)

别名:

(S)-2-甲基-1,4,5,6-四氢嘧啶-4-羧酸, 刺激物(B)

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关于此项目

经验公式(希尔记法):
C6H10N2O2
化学文摘社编号:
分子量:
142.16
UNSPSC Code:
24112111
NACRES:
NA.21
PubChem Substance ID:
EC Number:
431-910-1
Beilstein/REAXYS Number:
7288977
MDL number:
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Quality Level

assay

≥95.0% (HPLC)

form

powder

mol wt

142.16 g/mol

storage condition

dry at room temperature

color

white

solubility

methanol: soluble 10 mg/mL, clear, colorless to almost colorless

SMILES string

CC1=N[C@@H](CCN1)C(O)=O

InChI

1S/C6H10N2O2/c1-4-7-3-2-5(8-4)6(9)10/h5H,2-3H2,1H3,(H,7,8)(H,9,10)/t5-/m0/s1

InChI key

WQXNXVUDBPYKBA-YFKPBYRVSA-N

General description

四氢嘧啶(Ectoine), 全称4,5,6-四氢-2-甲基-4-嘧啶羧酸, 是一种两性氨基酸衍生物,作为相容性渗透保护溶质, 由好氧型、化能异养型和嗜盐性细菌生产, 抵抗渗透压胁迫、辐射和其他不利的 环境条件。

Application

该 四氢嘧啶的实际应用包括酶稳定、 抗炎处理、神经退行性疾病预防和其他 治疗用途。

Biochem/physiol Actions

四氢嘧啶可用作酶稳定剂,在温度变化下维持水化和减少酶变性。还可提高双链DNA的高温稳定性。

Other Notes

酶和生物大分子的稳定剂


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存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Adam Bownik et al.
Arhiv za higijenu rada i toksikologiju, 67(4), 260-265 (2016-12-30)
Ectoine is a compatible water molecule-binding solute (osmoprotectant) produced by several bacterial species in response to osmotic stress and unfavourable environmental conditions. This amino acid derivative can accumulate inside cells at high concentrations without interfering with natural processes and can
M.D. Vangala et al.
Bioforum, 23, 760-760 (2000)
Alexander S Reshetnikov et al.
Extremophiles : life under extreme conditions, 15(6), 653-663 (2011-10-06)
The genes of ectoine biosynthesis pathway were identified in six species of aerobic, slightly halophilic bacteria utilizing methane, methanol or methylamine. Two types of ectoine gene cluster organization were revealed in the methylotrophs. The gene cluster ectABC coding for diaminobutyric



全球贸易项目编号

货号GTIN
81619-10G-F04061832997810
81619-100G-F04061833646892
81619-1G-F04061832997827