90567
安替吡啉
reference material
别名:
2,3-二甲基-1-苯基-3-吡唑啉-5-酮, 非那宗
等级
reference material
方案
≥98.5% (qNMR)
≥99.0% (GC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
杂质
≤0.5% water
mp
109-111 °C (lit.)
应用
forensics and toxicology
pharmaceutical (small molecule)
包装形式
neat
SMILES字符串
CN1N(C(=O)C=C1C)c2ccccc2
InChI
1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3
InChI key
VEQOALNAAJBPNY-UHFFFAOYSA-N
基因信息
human ... PTGS1(5742)
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应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
[The use of antipyrine for assessing the enzymatic activity of the liver monooxygenase system (a review of the literature)].
A Kh Ashirmetov et al.
Laboratornoe delo, (1)(1), 16-20 (1990-01-01)
F Pautet et al.
Pathologie-biologie, 33(7), 777-780 (1985-09-01)
Antipyrine is widely used as a model compound to assess the hepatic metabolism in man. This drug is extensively metabolized by the hepatic microsomal drug-oxidizing system, into three main metabolites and six minor compounds of the phase I. The metabolite
Drugs and the liver. Part II. The role of the antipyrine test in drug metabolism studies.
M Hartleb
Biopharmaceutics & drug disposition, 12(8), 559-570 (1991-11-01)
[Antipyrine test in evaluating the detoxifying function of the liver in chronic diseases].
A S Loginov et al.
Terapevticheskii arkhiv, 54(12), 31-34 (1982-01-01)
Factors influencing antipyrine elimination.
I H Stevenson
British journal of clinical pharmacology, 4(3), 261-265 (1977-06-01)
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