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Merck
CN

93893

大黄酚

analytical standard

别名:

1,8-二羟基-3-甲氧基-6-甲基蒽醌, 6- O -甲基大黄素, 6-甲氧基大黄酸, 大黄素-3-甲醚, 大黄素甲醚, 蜈蚣苔素

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关于此项目

经验公式(希尔记法):
C16H12O5
化学文摘社编号:
分子量:
284.26
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
208-315-7
Beilstein/REAXYS Number:
6770499
MDL number:
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InChI key

FFWOKTFYGVYKIR-UHFFFAOYSA-N

InChI

1S/C16H12O5/c1-7-3-9-13(11(17)4-7)16(20)14-10(15(9)19)5-8(21-2)6-12(14)18/h3-6,17-18H,1-2H3

SMILES string

COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1

grade

analytical standard

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

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General description

Physcion is an anthraquinone derivative and is available as the active constituent of Chinese medicinal plants such as Rhubarb, Polygonum cuspidatum and Reynoutria multiflora. It exhibits various biological activities such as antitumor, antimicrobial, antifungal, antioxidant and antihuman cytomegalovirus activity.

Application

Physcion may be used as an analytical reference standard for the quantification of the analyte in medicinal plants, pharmaceutical preparations, vegetables, herbs and liquors using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

草药中存在的蒽醌衍生物。

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

农药列管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Occurrence of emodin, chrysophanol and physcion in vegetables, herbs and liquors. Genotoxicity and anti-genotoxicity of the anthraquinones and of the whole plants
Mueller O.S, et al.
Food And Chemical Toxicology, 37(5), 481-491 (1999)
Han-Jing Yan et al.
The American journal of Chinese medicine, 38(3), 473-483 (2010-05-27)
Fallopia multiflora (Thunb.) Harald, a traditional Chinese medicinal plant, is used in treating dizziness. In this study, the samples of F. multiflora from ten different locations were collected, and five bioactive components (2, 3, 5, 4'-tetrahydroxystilbene-2-O-beta-D-glucoside, emodin, emodin-8-O-beta-D-glucoside, physcion and
Ming-Yi Shen et al.
PloS one, 6(11), e27480-e27480 (2011-11-17)
Plants provide a rich source of lead compounds for a variety of diseases. A novel approach combining phytochemistry and chemotaxis assays was developed and used to identify and study the mechanisms of action of the active compounds in F. japonica
Simultaneous determination of five anthraquinones in medicinal plants and pharmaceutical preparations by HPLC with fluorescence detection
He D, et al.
Journal of Pharmaceutical and Biomedical Analysis, 49(4), 1123-1127 (2009)
Santosh Pandit et al.
Biofouling, 28(3), 279-287 (2012-03-23)
Polygonum cuspidatum is a plant with spreading rhizomes and numerous reddish-brown stems that has been used in Korean folk medicine to improve oral hygiene. Nevertheless, there are no reports related to its possible effect on the virulence of dental biofilms.

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