C2040
咳平 盐酸盐
analytical standard
别名:
氯哌斯丁
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关于此项目
经验公式（希尔记法）:
C20H24ClNO · HCl
化学文摘社编号:
分子量:
366.32
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
239-067-8
MDL number:
grade
analytical standard
Quality Level
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
SMILES string
Cl.Clc1ccc(cc1)C(OCCN2CCCCC2)c3ccccc3
InChI
1S/C20H24ClNO.ClH/c21-19-11-9-18(10-12-19)20(17-7-3-1-4-8-17)23-16-15-22-13-5-2-6-14-22;/h1,3-4,7-12,20H,2,5-6,13-16H2;1H
InChI key
UNPLRYRWJLTVAE-UHFFFAOYSA-N
Application
Cloperastine hydrochloride may be used as an analytical standard for the quantification of cloperastine in biological samples using liquid chromatography coupled to tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
[Effect of cloperastine on muco-ciliary clearance].
D Olivieri et al.
Archivio Monaldi per la tisiologia e le malattie dell'apparato respiratorio, 38(5-6), 219-223 (1983-09-01)
Yukoh Sakata et al.
International journal of pharmaceutics, 335(1-2), 12-19 (2006-11-23)
Tablets containing both paracetamol (PM) and cloperastine hydrochloride (CLH) in a combination formulation prepared by standard vertical granulation technology were found to have altered pharmaceutical properties. The hardness and disintegration time of tablets containing both PM and CLH gradually increased
Hao Li et al.
Journal of pharmaceutical and biomedical analysis, 51(3), 716-722 (2009-11-03)
A rapid and sensitive method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the simultaneous quantitation of paracetamol, caffeine, pseudoephedrine, chlorpheniramine and cloperastine in human plasma has been developed and validated. After sample preparation by liquid-liquid extraction, the analytes and
[Clinical study of a new antitussive: cloperastine].
D Olivieri et al.
Archivio Monaldi per la tisiologia e le malattie dell'apparato respiratorio, 38(5-6), 209-218 (1983-09-01)
Antonia García et al.
Journal of pharmaceutical and biomedical analysis, 61, 230-236 (2012-01-10)
The classification of an impurity of a drug substance as genotoxic means that the "threshold of toxicological concern" (TTC) value of 1.5 μg/day intake, considered to be associated with an acceptable risk, should be the admissible limit in the raw
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