D3281
二氟尼柳
analytical standard
别名:
5-(2,4-二氟苯基)水杨酸
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关于此项目
经验公式（希尔记法）:
C13H8F2O3
化学文摘社编号:
分子量:
250.20
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
245-034-9
MDL number:
grade
analytical standard
Quality Level
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
FC1=CC(F)=CC=C1C2=CC(C(O)=O)=C(O)C=C2
InChI
1S/C13H8F2O3/c14-8-2-3-9(11(15)6-8)7-1-4-12(16)10(5-7)13(17)18/h1-6,16H,(H,17,18)
InChI key
HUPFGZXOMWLGNK-UHFFFAOYSA-N
Gene Information
human ... ALB(213), PTGS1(5742), PTGS2(5743)
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Ellen Y Cotrina et al.
Journal of medicinal chemistry, 56(22), 9110-9121 (2013-10-24)
The amyloidogenic protein transthyretin (TTR) is thought to aggregate into amyloid fibrils by tetramer dissociation which can be inhibited by a number of small molecule compounds. Our analysis of a series of crystallographic protein-inhibitor complexes has shown no clear correlation
Frederick G Vogt et al.
Molecular pharmaceutics, 9(11), 3357-3374 (2012-09-27)
The solubility of drug molecules can often be improved through preparation and delivery of cyclodextrin (CD) inclusion complexes. These drug-oligosaccharide complexes can be prepared in solution and converted to the solid state via methods such as lyophilization and spray-drying, or
Stella Fountoulaki et al.
Journal of inorganic biochemistry, 105(12), 1645-1655 (2011-11-11)
Copper(II) complexes with the non-steroidal anti-inflammatory drug diflunisal in the presence of N,N-dimethylformamide or nitrogen donor heterocyclic ligands (pyridine, 1,10-phenanthroline, 2,2'-bipyridine or 2,2'-bipyridylamine) have been synthesized and characterized. The deprotonated diflunisal ligands are coordinated to Cu(II) ion through carboxylato oxygen
Teresa Mairal et al.
PloS one, 4(1), e4124-e4124 (2009-01-07)
The thyroid hormone and retinol transporter protein known as transthyretin (TTR) is in the origin of one of the 20 or so known amyloid diseases. TTR self assembles as a homotetramer leaving a central hydrophobic channel with two symmetrical binding
Maria Esther Zugasti et al.
Drug development and industrial pharmacy, 35(10), 1264-1270 (2009-06-27)
The influence of beta-cyclodextrin (beta-CD) polymers on drug release from hydroxypropyl methylcellulose (HPMC) matrices has not been reported in the literature. The influence of monomeric beta-CD and both soluble and insoluble beta-CD polymers on drug release from tablets containing either
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| D3281-5G | 04061833563069 |
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