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E1769

N-（3-二甲基氨基丙基）-N′-乙基碳二亚胺盐酸盐

Name: <I>N</I>-（3-二甲基氨基丙基）-<I>N</I>′-乙基碳二亚胺 盐酸盐
Brand: SIAL

BioXtra

别名:

N-乙基-N′ -（3-二甲基氨基丙基）碳二亚胺盐酸盐, EDAC, EDC, EDC 盐酸盐, WSC 盐酸盐

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关于此项目

经验公式（希尔记法）:

C₈H₁₇N₃ · HCl

化学文摘社编号:

25952-53-8

分子量:

191.70

NACRES:

NA.25

PubChem Substance ID:

24894433

UNSPSC Code:

12161700

EC Number:

247-361-2

MDL number:

MFCD00012503

Beilstein/REAXYS Number:

5764110

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属性

产品名称

N-（3-二甲基氨基丙基）-N′-乙基碳二亚胺盐酸盐, BioXtra

product line

BioXtra

Quality Level

200

form

powder

impurities

≤0.005% Phosphorus (P), ≤0.1% Insoluble matter

ign. residue

≤0.1%

mp

110-115 °C (lit.)

solubility

H₂O: 0.5 M, clear to very slightly hazy, colorless to very faintly yellow

anion traces

sulfate (SO₄^2-): ≤0.05%

cation traces

Al: ≤0.0005%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH₄⁺: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

storage temp.

−20°C

SMILES string

Cl.CCN=C=NCCCN(C)C

InChI

1S/C8H17N3.ClH/c1-4-9-8-10-6-5-7-11(2)3;/h4-7H2,1-3H3;1H

InChI key

FPQQSJJWHUJYPU-UHFFFAOYSA-N

说明

Application

N-(3-二甲基氨基丙基)-N′-乙基碳二亚胺盐酸盐已用于：

来自福尔马林固定石蜡包埋（FFPE）组织的小核糖核酸（RNA）种类的后固定和交联，用于荧光原位杂交（FISH）和免疫荧光（IF）信号
纳米纤维基质与小鼠肺组织提取物的交联
底物XNA寡核苷酸的激活

Biochem/physiol Actions

水溶性缩合试剂。EDAC通常用作与伯胺进行酰胺键合的羧基活化剂。另外，它能与磷酸基团反应。其已用于例如肽合成、将蛋白质与核酸交联、以及免疫缀合物的制备。通常，EDAC在不含缓冲剂的pH范围4.0-6.0的条件下使用。特别是，应避免使用胺和羧酸盐缓冲液。

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pictograms

GHS06,GHS08,GHS09

signalword

Danger

target_organs

Stomach,large intestine,lymph node

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

hcodes

H302,H311,H315,H317,H319,H373,H410

pcodes

P273 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338 - P314

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral

历史批次信息供参考:

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Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.

用于细胞膜片组织工程的基于聚N-异丙基丙烯酰胺的智能表面

组织工程已成为治疗受损或患病的器官和组织（例如血管和尿囊）的关键治疗工具。

Directed evolution of artificial enzymes (XNAzymes) from diverse repertoires of synthetic genetic polymers

Taylor AI and Holliger P

Nature Protocols, 10(10), 1625-1625 (2015)

Organ-derived coatings on electrospun nanofibers as ex vivo microenvironments

Fischer SN, et al.

Biomaterials, 32(2), 538-546 (2011)

Terminator-free template-independent enzymatic DNA synthesis for digital information storage.

Henry H Lee et al.

Nature communications, 10(1), 2383-2383 (2019-06-05)

DNA is an emerging medium for digital data and its adoption can be accelerated by synthesis processes specialized for storage applications. Here, we describe a de novo enzymatic synthesis strategy designed for data storage which harnesses the template-independent polymerase terminal

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全球贸易项目编号

货号	GTIN
E1769-5G	04061833602218
E1769-25G	04061833602201
E1769-10G	04061833602188
E1769-1G	04061833602195

主要文件

N-（3-二甲基氨基丙基）-N′-乙基碳二亚胺盐酸盐

BioXtra