G6895
格拉非宁
analytical standard
别名:
1-Glyceryl N-(7-chloro-4-quinolyl)anthranilate
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关于此项目
经验公式（希尔记法）:
C19H17ClN2O4
化学文摘社编号:
分子量:
372.80
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
223-315-7
MDL number:
grade
analytical standard
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
SMILES string
OCC(O)COC(=O)c1ccccc1Nc2ccnc3cc(Cl)ccc23
InChI
1S/C19H17ClN2O4/c20-12-5-6-14-17(7-8-21-18(14)9-12)22-16-4-2-1-3-15(16)19(25)26-11-13(24)10-23/h1-9,13,23-24H,10-11H2,(H,21,22)
InChI key
GWOFUCIGLDBNKM-UHFFFAOYSA-N
Gene Information
human ... PTGS1(5742), PTGS2(5743)
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
C Moesch et al.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 31(5), 329-333 (1993-05-01)
Glaphenine is an analgesic drug derived from anthranilic acid. We report the analytical procedures for stone analysis in three cases of common bile duct stones containing glaphenic acid, which developed in arthrosic patients treated for 13.7 +/- 5 years with
Bo Wen et al.
Drug metabolism and disposition: the biological fate of chemicals, 39(9), 1511-1521 (2011-06-02)
Glafenine (Privadol; 2,3-dihydroxypropyl 2-[(7-chloro-4-quinolinyl) amino]benzoate) is a non-narcotic analgesic agent widely used for the treatment of pains of various origins. Severe liver toxicity and a high incidence of anaphylaxis were reported in patients treated with glafenine, eventually leading to its
Renaud Robert et al.
Molecular pharmacology, 77(6), 922-930 (2010-03-05)
Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene, which encodes a cAMP-activated anion channel expressed in epithelial cells. The most common mutation Delta Phe508 leads to protein misfolding, retention by the endoplasmic reticulum