N8153
3-亚硝基苯酰胺
analytical standard, for drug analysis
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关于此项目
经验公式（希尔记法）:
C7H6N2O2
化学文摘社编号:
分子量:
150.13
UNSPSC Code:
41116107
PubChem Substance ID:
MDL number:
assay
≥98%
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
storage temp.
2-8°C
SMILES string
NC(=O)c1cccc(c1)N=O
InChI
1S/C7H6N2O2/c8-7(10)5-2-1-3-6(4-5)9-11/h1-4H,(H2,8,10)
InChI key
OZUBORKYZRYLSQ-UHFFFAOYSA-N
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
法规信息
新产品
此项目有
W G Rice et al.
Proceedings of the National Academy of Sciences of the United States of America, 90(20), 9721-9724 (1993-10-15)
The C-nitroso compound 3-nitrosobenzamide, which has been shown to remove zinc from the retroviral-type zinc finger of p7NC nucleocapsid proteins, inhibits acute infection of human immunodeficiency virus type 1 in cultured human lymphocytes. The attachment of the virus to lymphocytes
Akio Noguchi et al.
Nature chemical biology, 6(9), 641-643 (2010-08-03)
Although C-nitroso aromatic compounds have several bioactivities of medicinal interest, the biosynthetic enzymes involved in C-nitrosation have remained unknown until now. Here, we report the entire biosynthesis pathway of 4-hydroxy-3-nitrosobenzamide in Streptomyces murayamaensis, in which a tyrosinase-like copper-containing monooxygenase is
Jake W Ginsbach et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(27), 10793-10797 (2012-06-20)
The terminal step of 4-hydroxy-3-nitrosobenzamide biosynthesis in Streptomyces murayamaensis is performed by NspF, a mono-oxygenase that converts o-aminophenols to the corresponding nitroso product (hydroxyanilinase activity). Previous biochemical characterization of the resting form of NspF suggested that this enzyme belonged to
Pal I Bauer et al.
Biochemical pharmacology, 63(3), 455-462 (2002-02-21)
E-ras 20 tumorigenic malignant cells and CV-1 non-tumorigenic cells were treated with a drug combination of 4-iodo-3-nitrobenzamide (INO(2)BA) and buthionine sulfoximine (BSO). Growth inhibition of E-ras 20 cells by INO(2)BA was augmented 4-fold when cellular GSH content was diminished by
X Yu et al.
Chemical research in toxicology, 8(4), 586-590 (1995-06-01)
In vitro oxidation of the HIV-1 nucleocapsid protein p7 by the C-nitroso compound 3-nitrosobenzamide (NOBA) has been investigated. When reconstituted p7 was incubated with NOBA, three disulfide bonds were formed per molecule of p7, Cys 15-Cys 18, Cys 28-Cys 36
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