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Merck
CN

R2253

罗利环素

analytical standard

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关于此项目

经验公式(希尔记法):
C27H33N3O8
化学文摘社编号:
分子量:
527.57
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
212-031-9
MDL number:
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grade

analytical standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

[H][C@@]12C[C@@]3([H])C(=C(O)[C@]1(O)C(=O)C(C(=O)NCN4CCCC4)=C(O)[C@H]2N(C)C)C(=O)c5c(O)cccc5[C@@]3(C)O

InChI

1S/C27H33N3O8/c1-26(37)13-7-6-8-16(31)17(13)21(32)18-14(26)11-15-20(29(2)3)22(33)19(24(35)27(15,38)23(18)34)25(36)28-12-30-9-4-5-10-30/h6-8,14-15,20,31,33-34,37-38H,4-5,9-12H2,1-3H3,(H,28,36)/t14-,15-,20-,26+,27-/m0/s1

InChI key

HMEYVGGHISAPJR-IAHYZSEUSA-N

General description

Chemical structure: tetracycline

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M Vaverka et al.
Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 58(1-2), 98-103 (1991-03-01)
The role of antibiotics in the treatment and prevention of postoperative spondylodiscitis is still controversial. In a group of 15 patients operated on account of lumbar discopathy, the authors investigated the penetration of antibiotics into the intervertebral disc, in correlation
J Mertens et al.
HNO, 35(6), 262-264 (1987-06-01)
Gelatine sponge packs (Marbagelan) saturated in rolitetracycline (Reverin) were evaluated. The antimicrobiotic efficacy of the substance was determined in 26 packs before insertion and in 20 packs removed from the external ear meatus after varying periods. High concentrations of rolitetracycline
[Experimental animal and clinical studies of caries activity and progression in tetracycline-containing hard dental tissues. 1. Animal experiment studies].
G Radtke et al.
Zahn-, Mund-, und Kieferheilkunde mit Zentralblatt, 72(1), 11-16 (1984-01-01)
S Kobayashi et al.
The Japanese journal of antibiotics, 42(5), 1208-1215 (1989-05-01)
Combinations of cefotaxime (CTX) or other five beta-lactams with rolitetracycline (RTC) were examined using the checkerboard method for their synergistic effects against 27 strains of methicillin-resistant Staphylococcus aureus (MRSA), and the combination of CTX and RTC was further evaluated for
A D Widgerow et al.
South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie, 35(2), 88-92 (1997-05-01)
Fluid accumulation in a 'dead space' after surgery or trauma predisposes the area involved to delayed healing. The fluid may promote inflammatory mediators and other wound-modulating factors, which encourages the continued existence of the dead space. Tissue adhesion by means

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