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文件

B9050

Sigma-Aldrich

奥布卡因 盐酸盐

meets USP testing specifications

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别名:
4-氨基-3-丁氧基苯甲酸二乙基氨基乙基酯, 丁氧卡因 盐酸盐
经验公式（希尔记法）:
C17H28N2O3 · HCl
CAS号:
5987-82-6
分子量:
344.88
EC 号:
227-808-8
MDL编号:
MFCD00012512
PubChem化学物质编号:
24892118
NACRES:
NA.21

Agency

USP/NF
meets USP testing specifications

质量水平

200

形式

solid

应用

pharmaceutical (small molecule)

SMILES字符串

Cl[H].CCCCOc1cc(ccc1N)C(=O)OCCN(CC)CC

InChI

1S/C17H28N2O3.ClH/c1-4-7-11-21-16-13-14(8-9-15(16)18)17(20)22-12-10-19(5-2)6-3;/h8-9,13H,4-7,10-12,18H2,1-3H3;1H

InChI key

PRGUDWLMFLCODA-UHFFFAOYSA-N

基因信息

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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Ching-Hsia Hung et al.
Neuroscience letters, 454(3), 249-253 (2009-05-12)
Proxymetacaine and oxybuprocaine were clinically used for topical ocular anesthesia but never for spinal anesthesia, and therefore spinal anesthetic effects of proxymetacaine and oxybuprocaine were performed and compared with bupivacaine and lidocaine. After rats were injected intrathecally with proxymetacaine, oxybuprocaine
M M K Muqit et al.
The British journal of ophthalmology, 94(11), 1493-1498 (2010-06-19)
To evaluate pain responses following Pascal 20 ms multi-spot and 100 ms single-spot panretinal photocoagulation (PRP). Single-centre randomised clinical trial. 40 eyes of 24 patients with treatment-naive proliferative diabetic retinopathy randomised to 20 and 100 ms PRP under topical 0.4%
Shai Sandalon et al.
Documenta ophthalmologica. Advances in ophthalmology, 118(2), 101-108 (2008-07-31)
Topical anesthetics are recommended when electroretinograms (ERGs) are recorded using contact lens electrodes. However, these drugs act by blocking voltage-gated Na+ channels. Since such channels have been located in both the inner and outer retina of many species, topical anesthesia
Neal E Mecum et al.
Scientific reports, 10(1), 17225-17225 (2020-10-16)
Lacrimal gland excision (LGE) induced dry eye produces more severe corneal damage in female mice, yet signs of LGE-induced ocular pain and anxiety in male and female mice have not been characterized. Excision of either the extraorbital gland (single LGE)
Antonio Leccisotti et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 26(12), 942-948 (2010-02-20)
To evaluate the clinical effects of transepithelial corneal cross-linking (CXL) on keratoconic eyes pre-treated with substances enhancing epithelial permeability. Prospective, consecutive, single-masked, paired-eye study on 51 patients. The eye with more severe keratoconus was treated; the fellow eye served as
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