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Merck
CN

D4065

Supelco

地红霉素

analytical standard, for drug analysis

别名:

[9S(R)]-9-脱氧-11-脱氧-9,11-[亚氨[2-(2-甲氧基乙氧基)亚乙基]氧]红霉素；LY-237216

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关于此项目

经验公式（希尔记法）:
C42H78N2O14
化学文摘社编号:
62013-04-1
分子量:
835.07
MDL编号:
MFCD00865041
UNSPSC代码:
41116107
PubChem化学物质编号:
329798792

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质量水平

100

方案

≥95% (TLC)

表单

solid

分子量

apparent mol wt 835.1

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

forensics and toxicology
pharmaceutical (small molecule)
veterinary

包装形式

neat

SMILES字符串

CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C4N[C@@H](COCCOC)OC([C@H]4C)[C@]1(C)O

InChI

1S/C42H78N2O14/c1-15-29-42(10,49)37-24(4)32(43-30(56-37)21-52-17-16-50-13)22(2)19-40(8,48)36(58-39-33(45)28(44(11)12)18-23(3)53-39)25(5)34(26(6)38(47)55-29)57-31-20-41(9,51-14)35(46)27(7)54-31/h22-37,39,43,45-46,48-49H,15-21H2,1-14H3/t22-,23-,24+,25+,26-,27+,28+,29-,30-,31+,32+,33-,34+,35+,36-,37-,39+,40-,41+,42-/m1/s1

InChI key

WLOHNSSYAXHWNR-KZYCBHIHSA-N

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一般描述

Chemical structure: macrolide

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H317

预防措施声明

P280

危险分类

Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCG0791
MKCD2497
MKBV6004V
MKBV2310V
MKBQ6449V

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T Mazzei et al.
Antimicrobial agents and chemotherapy, 43(7), 1556-1559 (1999-07-02)
The pharmacokinetics of dirithromycin were determined over a 72-h period following oral administration of a single 500-mg dose to 8 healthy volunteers and to 16 cirrhotic patients (8 patients with class A cirrhosis and 8 patients with class B cirrhosis
Roger E Alexander et al.
Texas dental journal, 126(4), 326-333 (2009-05-29)
Erythromycins have been part of our armamentarium against selected bacterial infections since they were discovered in 1952 and approved by the Food and Drug Administration (FDA) in 1964. In 1991, two newer, long-acting erythromycin analogues, azythromycin (brand name: Zithromax) and
Bilgin Arda et al.
International journal of antimicrobial agents, 23(2), 204-207 (2004-03-12)
The efficacy of levofloxacin and dirithromycin, alone and in combination with rifampicin in the treatment of experimental brucellosis was investigated. Seventy adult white male mice were infected intraperitoneally with Brucella abortus S544 standard strain. Four of the animals were sacrificed
W B Shelley et al.
Journal of the American Academy of Dermatology, 40(1), 69-72 (1999-01-28)
In an open uncontrolled study of 3 patients with balanitis xerotica obliterans we have observed significant improvement after long-term systemic antibiotic therapy. Two of the patients noticed softening of the skin as well as disappearance of pruritus, tenderness, and inflammatory
C Leroyer et al.
Respiration; international review of thoracic diseases, 65(5), 381-385 (1998-10-23)
Since a high tissue penetration of dirithromycin (D) has been assessed in early studies, the aims of this study were to determine D concentrations in bronchial mucosa and secretions in patients suffering from an acute exacerbation of chronic bronchitis (AECB)
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