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Merck
CN

E3764

Supelco

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analytical standard

别名:

1-乙基-6-氟-1,4-二氢-4-氧代-7-(1-哌嗪基)-1,8-萘啶-3-羧酸

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关于此项目

经验公式（希尔记法）:
C15H17FN4O3
化学文摘社编号:
74011-58-8
分子量:
320.32
MDL编号:
MFCD00133308
UNSPSC代码:
41116107
PubChem化学物质编号:
329799054

主要文件

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等级

analytical standard

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

forensics and toxicology
pharmaceutical (small molecule)
veterinary

包装形式

neat

储存温度

2-8°C

SMILES字符串

CCN1C=C(C(O)=O)C(=O)c2cc(F)c(nc12)N3CCNCC3

InChI

1S/C15H17FN4O3/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20/h7-8,17H,2-6H2,1H3,(H,22,23)

InChI key

IDYZIJYBMGIQMJ-UHFFFAOYSA-N

基因信息

human ... CYP1A2(1544)

一般描述

Chemical structure: fluoroquinolone

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生化/生理作用

亲水性氟喹诺酮抗生素。NorA（金黄色葡萄球菌内的一种能量依赖性药外排泵）的底物。NorA 表达是造成某些耐药菌感染的原因。

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
109K1067

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. In what solvent can Product E3764, Enoxacin, be reconstituted?

    This product may be reconstituted in DMSO at 8 mg/mL.

  6. What class of antibiotics does Product E3764, Enoxacin, belong to?

    Enoxacin is a broad spectrum fluoroquinolone antibiotic used in the treatment of urinary tract infections.  

  7. What working concentration has been reported for Product E3764, Enoxacin?

    Enoxacin has been used at 1 mM on cultured Calu-3 cells to inhibit transepithelial transport of ciprofloxacin, as reported in Antimicrob. Agents Chemother. 41(12), 2693-2698 (1997).

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Xuqiang Liu et al.
Biomaterials, 35(22), 5721-5730 (2014-04-29)
The aim of this study was to assess the effect of enoxacin on osteoclastogenesis and titanium particle-induced osteolysis. Wear particles liberated from the surface of prostheses are associated with aseptic prosthetic loosening. It is well established that wear particles induce
Julien Poissy et al.
Antimicrobial agents and chemotherapy, 54(11), 4765-4771 (2010-09-02)
The prevalence of extensively drug-resistant tuberculosis (XDR-TB), defined as TB that is resistant to isoniazid, rifampin, fluoroquinolones, and aminoglycosides, is rising worldwide. The extent of Mycobacterium tuberculosis resistance to fluoroquinolones depends on the mutation in the DNA gyrase, the only
Fuxing Liu et al.
Frontiers in bioengineering and biotechnology, 8, 131-131 (2020-04-08)
Recently, many studies have demonstrated that microRNAs (miRNAs) are new small molecule drug targets. Identifying small molecule-miRNA associations (SMiRs) plays an important role in finding new clues for various human disease therapy. Wet experiments can discover credible SMiR associations; however
Ghazanfar Ali Khan et al.
PloS one, 8(6), e62712-e62712 (2013-07-11)
Antibiotic resistance (AR) is a global phenomenon that has severe epidemiological ramifications world-wide. It has been suggested that antibiotics that have been discharged into the natural aquatic environments after usage or manufacture can promote the occurrence of antibiotic resistance genes
Julia Breger et al.
PLoS pathogens, 3(2), e18-e18 (2007-02-06)
There is an urgent need for the development of new antifungal agents. A facile in vivo model that evaluates libraries of chemical compounds could solve some of the main obstacles in current antifungal discovery. We show that Candida albicans, as
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