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Merck
CN

F1427

氟苯尼考

analytical standard, for drug analysis

别名:

SCH-25298, [R-(R*,S*)]-2,2-二氯-N-[1-(氟代甲基)-2-羟基-2-[4-(甲磺酰基)苯基]乙基]乙酰胺, 氟洛芬, 氟苯尼考

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关于此项目

经验公式(希尔记法):
C12H14Cl2FNO4S
化学文摘社编号:
分子量:
358.21
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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Quality Level

form

solid

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl

InChI

1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1

InChI key

AYIRNRDRBQJXIF-NXEZZACHSA-N

General description

Florfenicol is a broad-spectrum amphenicol antibiotic used against diseases affecting domestic and wild animals.

Application

The analytical standard can be used as follows:
  • To measure florfenicol and its main metabolite florfenicol amine in tilapia meat by solid phase extraction (SPE) and ultra high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)
  • Multi-residue analysis of three amfenicols in animal feed samples by HPLC-MS/MS method, following European Commission Decision 2002/657/EC(2)Determination of florfenicol in different animal feedstuff samples by thin layer chromatography (TLC) coupled with HPLC-UV detection
  • Residue analysis of florfenicol in broiler meat and liver samples by a reversed phase-HPLC method in combination with UV detection at 223 nm
  • Competitive indirect-chemiluminescent enzyme-linked immunosorbent assay (CL-ELISA) based quantitative analysis of florfenicol and its major metabolite florfenicol amine in chicken muscle samples, validated as per Commission Decision 2002/657/EC

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.


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pictograms

Health hazardEnvironment

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 1

target_organs

Liver,Brain,Testes,Spinal cord,Blood,gallbladder

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品

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Sergio Contreras-Lynch et al.
Frontiers in microbiology, 8, 1255-1255 (2017-07-22)
This paper presents a validated protocol, using a novel, specifically formulated medium, to perform broth microdilution antimicrobial susceptibility assays of the salmonid bacterial pathogen
Ye Wang et al.
Biosensors & bioelectronics, 87, 508-513 (2016-09-07)
Herein, a smart single-stranded DNA binding protein (SSB)-assisted fluorescence aptamer switch based on fluorescence resonance energy transfer (FRET) was designed. The FRET switch was synthesized by connecting SSB labeled quantum dots (QDs@SSB) as donor with aptamer (apt) labeled gold nanoparticles
Jacob M Swift et al.
Foodborne pathogens and disease, 14(3), 160-166 (2017-01-12)
Small ruminants have been implicated in outbreaks of Escherichia coli O157:H7 at livestock exhibitions throughout the United States. Additionally, goat meat or milk may serve as a reservoir for foodborne transmission of the organism. These associations highlight the public health



全球贸易项目编号

货号GTIN
F1427-500MG04061835564101