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F1427

氟苯尼考

Name: 氟苯尼考
Brand: SIAL

analytical standard, for drug analysis

别名:

SCH-25298, [R-(R*,S*)]-2,2-二氯-N-[1-(氟代甲基)-2-羟基-2-[4-(甲磺酰基)苯基]乙基]乙酰胺, 氟洛芬, 氟苯尼考

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关于此项目

经验公式（希尔记法）:

C₁₂H₁₄Cl₂FNO₄S

化学文摘社编号:

73231-34-2

分子量:

358.21

NACRES:

NA.24

PubChem Substance ID:

329799680

UNSPSC Code:

41116107

MDL number:

MFCD00864834

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属性

Quality Level

100

form

solid

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl

InChI

1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1

InChI key

AYIRNRDRBQJXIF-NXEZZACHSA-N

说明

General description

Florfenicol is a broad-spectrum amphenicol antibiotic used against diseases affecting domestic and wild animals.

Application

The analytical standard can be used as follows:

To measure florfenicol and its main metabolite florfenicol amine in tilapia meat by solid phase extraction (SPE) and ultra high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)
Multi-residue analysis of three amfenicols in animal feed samples by HPLC-MS/MS method, following European Commission Decision 2002/657/EC(2)Determination of florfenicol in different animal feedstuff samples by thin layer chromatography (TLC) coupled with HPLC-UV detection
Residue analysis of florfenicol in broiler meat and liver samples by a reversed phase-HPLC method in combination with UV detection at 223 nm
Competitive indirect-chemiluminescent enzyme-linked immunosorbent assay (CL-ELISA) based quantitative analysis of florfenicol and its major metabolite florfenicol amine in chicken muscle samples, validated as per Commission Decision 2002/657/EC

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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pictograms

GHS08,GHS09

signalword

Danger

hcodes

H361fd,H372,H410

pcodes

P202 - P260 - P264 - P273 - P280 - P308 + P313

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 1

target_organs

Liver,Brain,Testes,Spinal cord,Blood,gallbladder

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品

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Whole blood transcriptomic analysis of beef cattle at arrival identifies potential predictive molecules and mechanisms that indicate animals that naturally resist bovine respiratory disease.

Matthew A Scott et al.

PloS one, 15(1), e0227507-e0227507 (2020-01-14)

Bovine respiratory disease (BRD) is a multifactorial disease complex and the leading infectious disease in post-weaned beef cattle. Clinical manifestations of BRD are recognized in beef calves within a high-risk setting, commonly associated with weaning, shipping, and novel feeding and

Evaluation of 27 different biochars for potential sequestration of antibiotic residues in food animal production environments

Mitchell M S, et al.

Journal of Environmental Chemical Engineering, 3(1), 162-169 (2015)

Joren De Smet et al.

Frontiers in pharmacology, 9, 1265-1265 (2018-11-22)

Florfenicol, which is licensed for veterinary use only, proves to be a potent antimicrobial for treatment of respiratory disease. However, the subsequent exposure of the gut microbiota to florfenicol is not well described. Hence, the effect of various administration protocols

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全球贸易项目编号

货号	GTIN
F1427-500MG	04061835564101