F1427
氟苯尼考
analytical standard, for drug analysis
别名:
SCH-25298, [R-(R*,S*)]-2,2-二氯-N-[1-(氟代甲基)-2-羟基-2-[4-(甲磺酰基)苯基]乙基]乙酰胺, 氟洛芬, 氟苯尼考
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关于此项目
经验公式（希尔记法）:
C12H14Cl2FNO4S
化学文摘社编号:
分子量:
358.21
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
质量水平
表单
solid
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
包装形式
neat
SMILES字符串
CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl
InChI
1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1
InChI key
AYIRNRDRBQJXIF-NXEZZACHSA-N
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一般描述
Florfenicol is a broad-spectrum amphenicol antibiotic used against diseases affecting domestic and wild animals.
应用
The analytical standard can be used as follows:
- To measure florfenicol and its main metabolite florfenicol amine in tilapia meat by solid phase extraction (SPE) and ultra high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)
- Multi-residue analysis of three amfenicols in animal feed samples by HPLC-MS/MS method, following European Commission Decision 2002/657/EC(2)Determination of florfenicol in different animal feedstuff samples by thin layer chromatography (TLC) coupled with HPLC-UV detection
- Residue analysis of florfenicol in broiler meat and liver samples by a reversed phase-HPLC method in combination with UV detection at 223 nm
- Competitive indirect-chemiluminescent enzyme-linked immunosorbent assay (CL-ELISA) based quantitative analysis of florfenicol and its major metabolite florfenicol amine in chicken muscle samples, validated as per Commission Decision 2002/657/EC
其他说明
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
警示用语：
Danger
危险声明
危险分类
Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 1
靶器官
Liver,Brain,Testes,Spinal cord,Blood,gallbladder
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
Sergio Contreras-Lynch et al.
Frontiers in microbiology, 8, 1255-1255 (2017-07-22)
This paper presents a validated protocol, using a novel, specifically formulated medium, to perform broth microdilution antimicrobial susceptibility assays of the salmonid bacterial pathogen
Abdolhossein Jangaran Nejad et al.
Veterinary research forum : an international quarterly journal, 8(4), 327-331 (2018-01-13)
The aim of this study was to evaluate pharmacokinetic profiles of florfenicol after a single dose of intravenous (5.00 mg kg
Ye Wang et al.
Biosensors & bioelectronics, 87, 508-513 (2016-09-07)
Herein, a smart single-stranded DNA binding protein (SSB)-assisted fluorescence aptamer switch based on fluorescence resonance energy transfer (FRET) was designed. The FRET switch was synthesized by connecting SSB labeled quantum dots (QDs@SSB) as donor with aptamer (apt) labeled gold nanoparticles
Peizhen Li et al.
Frontiers in cellular and infection microbiology, 10, 369-369 (2020-09-10)
Bacterial resistance to antibiotics has become an important concern for public health. This study was aimed to investigate the characteristics and the distribution of the florfenicol-related resistance genes in bacteria isolated from four farms. A total of 106 florfenicol-resistant Gram-negative
Shih-Wei Wu et al.
Toxins, 12(10) (2020-10-08)
A two-analyte immunochromatographic strip (immunostrip) was developed for the simultaneous detection of aflatoxin M1 (AFM1) and chloramphenicol (CAP) in milk. Protein conjugates (AFM1-ovalbumin (OVA) and CAP-OVA) and goat anti-rabbit IgG were respectively drawn on nitrocellulose membrane as two test lines
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