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Merck
CN

P4554

丙美卡因 盐酸盐

analytical standard

别名:

Proxymetacaine hydrochloride

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关于此项目

经验公式(希尔记法):
C16H26N2O3 · HCl
化学文摘社编号:
分子量:
330.85
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
227-541-7
MDL number:
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产品名称

丙美卡因 盐酸盐, analytical standard

InChI key

BFUUJUGQJUTPAF-UHFFFAOYSA-N

InChI

1S/C16H26N2O3.ClH/c1-4-10-20-15-8-7-13(12-14(15)17)16(19)21-11-9-18(5-2)6-3;/h7-8,12H,4-6,9-11,17H2,1-3H3;1H

SMILES string

Cl.CCCOc1ccc(cc1N)C(=O)OCCN(CC)CC

grade

analytical standard

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

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Biochem/physiol Actions

眼用局部麻醉药

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Proparacaine hydrochloride is a topical ocular anesthetic, which is commonly used in pediatric patients.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Gregory R Blaha et al.
Retina (Philadelphia, Pa.), 31(3), 535-539 (2010-11-26)
To compare the effectiveness of four different anesthetic methods for intravitreal injection. Twenty-four patients each received four intravitreal injections using each of four types of anesthesia (proparacaine, tetracaine, lidocaine pledget, and subconjunctival injection of lidocaine) in a prospective, masked, randomized
Mani Baskaran et al.
Investigative ophthalmology & visual science, 55(11), 7669-7673 (2014-10-23)
To evaluate a novel software capable of automatically grading angle closure on EyeCam angle images in comparison with manual grading of images, with gonioscopy as the reference standard. In this hospital-based, prospective study, subjects underwent gonioscopy by a single observer
Ditipriya R Mukhopadhyay et al.
Journal of cataract and refractive surgery, 37(5), 907-913 (2011-03-23)
To assess the effect of a combination of proparacaine 0.50%-sodium fluorescein 0.25% and ultrasound (US) pachymetry on central and midperipheral corneal thickness. School of Optometry and Vision Sciences, Cardiff University, Cardiff, Wales, United Kingdom. Case series. Topographic measurements of corneal
Miriam L Conway et al.
Journal of cataract and refractive surgery, 36(2), 268-272 (2010-02-16)
To evaluate blood-flow responses before and after microkeratome application. School of Life and Health Sciences, Aston University, Birmingham, United Kingdom. Hemodynamic responses were measured in eyes of healthy volunteers before and after transient elevation in intraocular pressure (IOP) resulting from
M Mehta et al.
Journal of perinatology : official journal of the California Perinatal Association, 30(11), 731-735 (2010-03-20)
The efficacy of topical anesthesia during retinopathy of prematurity (ROP) screening has been a controversial issue. To determine the efficacy of proparacaine eye drops (0.5%), we compared the Premature Infant Pain Profile (PIPP) scores in 40 preterm infants undergoing ROP

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