S5632
磺胺甲二唑
analytical standard, ≥99% (HPLC)
别名:
4-氨基-N-(5-甲基-1,3,4-噻二唑-2-基)苯磺酰胺, N1-(5-甲基-1,3,4-噻二唑-2-基)磺胺
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关于此项目
经验公式（希尔记法）:
C9H10N4O2S2
化学文摘社编号:
分子量:
270.33
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
205-641-1
Beilstein/REAXYS Number:
255002
MDL number:
InChI key
VACCAVUAMIDAGB-UHFFFAOYSA-N
InChI
1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)
SMILES string
Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1
grade
analytical standard
agency
EPA 1694
assay
≥99% (HPLC)
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
clinical testing
format
neat
storage temp.
2-8°C
Quality Level
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Application
Sulfamethizole may be used as a reference standard to examine the antibiotic remnants in honey by multianalyte/multiclass ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Sulfamethizole is an antibacterial drug used in the treatment of the urinary tract infections.
Janez Seliger et al.
Physical chemistry chemical physics : PCCP, 12(40), 13007-13019 (2010-09-08)
The 1,3,4-thiadiazole derivatives (2-amino-1,3,4-thiadiazole, acetazolamide, sulfamethizole) have been studied experimentally in the solid state by (1)H-(14)N NQDR spectroscopy and theoretically by Density Functional Theory (DFT). The specific pattern of the intra and intermolecular interactions in 1,3,4-thiadiazole derivatives is described within
Stephen P Mezyk et al.
The journal of physical chemistry. A, 111(37), 9019-9024 (2007-08-25)
Absolute rate constants and degradation efficiencies for hydroxyl radical and hydrated electron reactions with four different sulfa drugs in water have been evaluated using a combination of electron pulse radiolysis/absorption spectroscopy and steady-state radiolysis/high-performance liquid chromatography measurements. For sulfamethazine, sulfamethizole
Development of a rapid method for the determination of antibiotic residues in honey using UPLC-ESI-MS/MS.
Kivrak I, et al.
Food Sci. Technol., 36(1), 90-96 (2016)
Coordination chemistry of sulfamethizole: crystal structures of [Cu (sulfamethizolate) 2 (py) 2 (OH 2)]? H 2 O,[M (sulfamethizolate) 2 (py) 2 (OH 2) 2][M= Co and Ni] and {Cu (sulfamethizolate) 2 (dmf) 2}?.
Borras E, et al.
Polyhedron, 19(15), 1859-1866 (2000)
Tony L Yaksh et al.
Anesthesiology, 108(5), 938-949 (2008-04-24)
Intrathecal N-methyl-d-aspartate antagonists have antihyperalgesic efficacy. The authors examined toxicity in a canine model of chronic lumbar intrathecal infusion. Dogs (10-16 kg) were prepared with lumbar intrathecal catheters connected to vest-mounted pumps (100 microl/h). In phase 1, stepwise incrementations in
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