S5632
磺胺甲二唑
analytical standard, ≥99% (HPLC)
别名:
4-氨基-N-(5-甲基-1,3,4-噻二唑-2-基)苯磺酰胺, N1-(5-甲基-1,3,4-噻二唑-2-基)磺胺
等级
analytical standard
质量水平
Agency
EPA 1694
方案
≥99% (HPLC)
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
clinical testing
包装形式
neat
储存温度
2-8°C
SMILES字符串
Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1
InChI
1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)
InChI key
VACCAVUAMIDAGB-UHFFFAOYSA-N
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一般描述
Sulfamethizole is an antibacterial drug used in the treatment of the urinary tract infections.
应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfamethizole may be used as a reference standard to examine the antibiotic remnants in honey by multianalyte/multiclass ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method.
Coordination chemistry of sulfamethizole: crystal structures of [Cu (sulfamethizolate) 2 (py) 2 (OH 2)]? H 2 O,[M (sulfamethizolate) 2 (py) 2 (OH 2) 2][M= Co and Ni] and {Cu (sulfamethizolate) 2 (dmf) 2}?.
Borras E, et al.
Polyhedron, 19(15), 1859-1866 (2000)
Development of a rapid method for the determination of antibiotic residues in honey using UPLC-ESI-MS/MS.
Kivrak I, et al.
Food Sci. Technol., 36(1), 90-96 (2016)
Ali Md Ahad et al.
Bioorganic & medicinal chemistry, 19(6), 2046-2054 (2011-03-01)
Disruption of the phosphatidylinositol 3-kinase/AKT signaling pathway can lead to apoptosis in cancer cells. Previously we identified a lead sulfonamide that selectively bound to the pleckstrin homology (PH) domain of AKT and induced apoptosis when present at low micromolar concentrations.
Robert R Muder
Seminars in respiratory and critical care medicine, 28(6), 672-677 (2007-12-21)
Stenotrophomonas (Xanthomonas) maltophilia is a nonfermentative, gram-negative bacillus that is widely distributed in natural and human-made environments. In the nonhospital setting it is an uncommon pathogen, typically causing soft tissue infection of contaminated wounds. In the hospital setting, particularly among
Mark R Sannes et al.
The Journal of infectious diseases, 197(3), 430-434 (2008-01-11)
To determine whether poultry contact/consumption predicts colonization with antimicrobial-resistant Escherichia coli, 567 newly hospitalized patients and 100 vegetarians were assessed microbiologically and epidemiologically. Multivariable analysis showed that poultry contact/consumption, other dietary habits, and antimicrobial use did not significantly predict resistance.
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