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Merck
CN

S7007

Supelco

磺胺地索辛

98.0-102.0%

别名:

4-氨基-N-(2,6-二甲氧-4-嘧啶基)苯磺酰胺

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关于此项目

经验公式(希尔记法):
C12H14N4O4S
CAS Number:
分子量:
310.33
Beilstein:
306856
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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质量水平

方案

98.0-102.0%

表单

powder

技术

HPLC: suitable
gas chromatography (GC): suitable

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

应用

forensics and toxicology
pharmaceutical (small molecule)

作用机制

DNA synthesis | interferes
enzyme | inhibits

储存温度

2-8°C

SMILES字符串

COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1

InChI

1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)

InChI key

ZZORFUFYDOWNEF-UHFFFAOYSA-N

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一般描述

化学结构:磺胺

应用

有关适用仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务部门。

生化/生理作用

通过抑制二氢叶酸合成酶阻断二氢叶酸合成的磺胺类抗生素。
作用方式:在原核生物中抑制叶酸合成。
抗菌谱:革兰氏阳性菌、革兰氏阴性菌、衣原体
抗性机理:二氢叶酸合成酶或叶酸合成替代路径的改变。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Annie von Eyken et al.
Journal of the American Society for Mass Spectrometry, 30(5), 765-777 (2019-03-17)
Non-targeted screening (e.g., suspected-target) is emerging as an attractive tool to investigate the occurrence of contaminants in food. The sample preparation and instrument analysis steps are known to influence the identification of analytes with non-targeted workflows, especially for complex matrices.
Masamichi Nakayama et al.
Colloids and surfaces. B, Biointerfaces, 99, 12-19 (2011-10-07)
Diblock copolymer comprising thermoresponsive poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide) (PIPAAm-co-DMAAm) and hydrophobic poly(benzyl methacrylate) blocks was prepared by reversible addition-fragmentation chain transfer radical polymerization. Terminal functionalization of thermoresponsive blocks with either pH-responsive sulfadimethoxine (SD) or hydroxyl groups was performed through coupling reactions with thiol
Kyung-Mi Song et al.
Biosensors & bioelectronics, 33(1), 113-119 (2012-01-17)
A polymer-based aptasensor, which consisted of fluorescein amidite (FAM)-modified aptamers and coordination polymer nanobelts (CPNBs), was developed utilizing the fluorescence quenching effect to detect sulfadimethoxine residue in food products. A single-stranded DNA (ssDNA) aptamer, which was a specific bio-probe for
Ailiang Chen et al.
Biosensors & bioelectronics, 42, 419-425 (2012-12-12)
Quickly and sensitively detection of antibiotic residues in animal products often requires time-consuming techniques and expensive instrumentation. To address these limitations, a high sensitive aptasensor for sulfadimethoxine (SDM) using unmodified gold nanoparticles (AuNPs) was developed in the present study. The
Dan Liu et al.
Chemical & pharmaceutical bulletin, 59(1), 63-71 (2011-01-08)
Recently, dendrimers have been widely used in medical applications such as drug delivery and gene transfection. In this study, a pH-sensitive diblock copolymer of poly(methacryloyl sulfadimethoxine) (PSD) and polyethylene glycol (PEG) modified by lactose (LA-PEG-b-PSD) was synthesized. The pK(a) value

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